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Wound Dehiscence clinical trials

View clinical trials related to Wound Dehiscence.

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NCT ID: NCT06373900 Completed - Wound Heal Clinical Trials

Wound Closure After Total Knee Arthroplasty: Comparison of Polypropylene and Polyglactin 910 Suture.

Start date: February 13, 2022
Phase: N/A
Study type: Interventional

Comparison of wound complication and scar formation in patient undergone bilateral total knee replacement comparison between polypropylene and polyglactin 910 suture. patient randomised according to SNOS protocol into group A and B for their right and left knee closure with each suture. patient followed on 3rd, 7th, 15th and 30th post operative day for wound healing, wound dehiscence and scar formation.

NCT ID: NCT06337292 Not yet recruiting - Wound Heal Clinical Trials

Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures: A Multicenter Randomized Controlled Trial

iVAC
Start date: May 1, 2024
Phase: Phase 3
Study type: Interventional

This is a multi-center, pragmatic, parallel arm randomized controlled trial (RCT) of 352 patients with high-risk open or closed tibial plateau fracture, high-risk open or closed tibial pilon fracture, or open tibial shaft fracture with incision >3cm. Eligible participants will be randomized to receive either incisional negative pressure wound therapy (NPWT) or a non-suction standard-of-care wound dressing for their definitive wound management. The primary outcome will be a composite outcome to evaluate clinical status 3 months after randomization. The secondary outcomes will independently assess the components of the primary outcome.

NCT ID: NCT06220344 Completed - Wound Infection Clinical Trials

Honey Dressing - A Preventive Procedure for Post-Surgical Site Infection.

Start date: December 2, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this clinical trial is to compare the wound healing in the participants who underwent the clean surgical procedure, by applying honey dressing and common Iodine solution dressing, participants will have no other co-morbidities like Diabetes, Anemia, etc. which can make the results biased. The main questions it aims to answer are: - Do the iodine solutions are enough to counter the infections caused by resistant strains of bacteria? - What is the efficacy and efficiency of honey dressing in wound care? Participants will be tasked to - Ensure strict follow-up in the hospital dressing room - Half of the participants will apply common iodine solution dressing and the other half will be applied honey dressing. Researchers will compare Iodine dressing (Control group) with Honey dressing (Experimental group) to see if Honey dressing is better in the prevention of post-surgery wound infection and if it is cost-efficient and its efficacy.

NCT ID: NCT05963477 Completed - Wound Dehiscence Clinical Trials

Pediatric Post-operative Abdominal Wound Dehiscence in Association With Midline vs Other Incisions: A Prospective Cohort Study

Start date: November 1, 2018
Phase:
Study type: Observational

This study is designed to see different abdominal incisions complication among neonates, infants and children and to find risk factors for developing wound dehiscence

NCT ID: NCT05830162 Recruiting - Infections Clinical Trials

Oral Antibiotics After Obstetric Perineal Tear

REPAIR
Start date: March 21, 2023
Phase: Phase 4
Study type: Interventional

The purpose of this study is to investigate if 3 dose of oral antibiotics administrated the first day after a vaginal delivery with a second degree obstetric tear will decrease the risk of infection and/or wound dehiscence compared to women with 3 doses of placebo treatment.

NCT ID: NCT05513222 Completed - Wound Dehiscence Clinical Trials

Flipped Autograft for Treating Surgical Wound Dehiscence

Start date: July 22, 2021
Phase: N/A
Study type: Interventional

This case report describes a novel technique for management of peri-implant wound dehiscence that involves using auto graft from the same surgical site to seal the dehiscence defect.

NCT ID: NCT05338281 Withdrawn - Breast Cancer Clinical Trials

NPWT for Abdominal Incisions in DIEP Reconstructions: A RCT

NPWTinDIEP
Start date: September 2023
Phase: N/A
Study type: Interventional

The current study is a single center randomized control trial that will examine the effect of closed incision negative pressure wound therapy (ciNPT) versus conventional dressing on abdominal incision in a deep inferior epigastric perforator (DIEP) flap based reconstruction. Patients will be followed by 30 days post-operatively to compare outcomes including the rate of surgical site infection, seroma, and the scar quality.

NCT ID: NCT05234632 Terminated - Pressure Ulcer Clinical Trials

Study to Evaluate the PICO 14 Negative Pressure Wound Therapy System in the Management of Acute and Chronic Wounds

PICO14
Start date: September 22, 2020
Phase: N/A
Study type: Interventional

This is a prospective, multi-center, open label study evaluating the performance of PICO14 NPWT in the management of chronic open wounds (pressure ulcers, venous leg ulcers, diabetes related foot ulcers), dehisced surgical wounds and closed surgical incisions. The study comprises the Post Market Clinical Follow-up (PMCF) for a new variant of an established product. PICO 14 is based on another dressing called PICO. The primary objective is to evaluate functional performance of PICO 14 through verification of delivery of negative pressure and wound exudate management.

NCT ID: NCT04681378 Completed - Cesarean Section Clinical Trials

A New Technique for Uterine Incision Closure at The Time of Cesarean Section: Does it Make a Difference

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this study was to compare the short term operative outcomes of three different surgical techniques for uterine incision closure during cesarean section (CS). This trial enrolled 120 patients scheduled for primary cesarean delivery. Patients were randomized into either classical double layer uterine closure, purse string double layer uterine closure (Turan), or our new approach of uterine closure (double layer step up-step down technique). For short term comparison, transvaginal ultrasonography was planned for all patients 6 weeks after surgery. Compared to group II and Group III, residual myometrial thickness was significantly thinner in group I (P< 0.001). The number of patients with uterine niche was 10 (50% of all scar defects) in group I whereas it was 4 (20%) in group II and 6 (30%) in group III. Operative time was significantly longer in group II (P< 0.001). This led to our conclusion that Turan technique and our new approach are associated with thicker myometrial thickness and less frequency of uterine scar defect than classical double layer uterine incision closure; however, our approach takes less operative time.

NCT ID: NCT04434820 Completed - Wound Dehiscence Clinical Trials

External Negative Pressure Dressing System vs. Traditional Wound Dressing for Cesarean Section Incision in Obese Women.

Start date: August 3, 2020
Phase: N/A
Study type: Interventional

Obesity is associated with increased cesarean section delivery rates and surgical site infections with associated increased post-operative morbidity, post-operative pain and length of hospital stay. Negative pressure wound therapy (NPWT) technology could be used as a prophylactic measure to reduce surgical site infections in obese women undergoing cesarean section by immediate postoperative application in clean-contaminated, closed surgical incisions.