Neonatal Abstinence Syndrome Clinical Trial
Official title:
Feasibility of Auricular Acupressure as an Adjunct Treatment for Neonatal Abstinence Syndrome (NAS)
This study will assess the feasibility of implementing auricular acupressure as an additional non-pharmacologic therapy for neonates at risk for developing neonatal abstinence syndrome (NAS) at Monroe Carrell Jr Children's Hospital at Vanderbilt University Medical Center (VUMC).
NAS is a condition in which newborns experience withdrawal symptoms as a result of in utero
exposure to opioids and/or other substances ingested by the mother. The condition has
significantly risen over the past 20 years. First line treatments for NAS involve the
maximization of non-pharmacologic therapies. NAS management focuses on reducing or
eliminating the need for medication management to prevent further developmental
complications, promote maternal bonding, and reduce hospital length of stay.
Auricular acupuncture has been used for the treatment of addiction and has demonstrated
efficacy in the adult population. Current evidence suggests that acupuncture is safe and
beneficial for multiple conditions that impact neonatal and pediatric populations including
NAS. Acupressure is a less invasive therapy and may serve as an additional
non-pharmacological adjunct to ease the severe discomfort of withdrawal in neonates at risk
for NAS.
This study will assess the feasibility of implementing auricular acupressure as an additional
non-pharmacologic therapy for neonates at risk for developing neonatal abstinence syndrome
(NAS) at Monroe Carrell Jr Children's Hospital at Vanderbilt University Medical Center
(VUMC).
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01965704 -
Can Ondansetron Prevent Neonatal Abstinence Syndrome (NAS) in Babies Born to Narcotic-dependent Women
|
Phase 2 | |
| Completed |
NCT03890562 -
Assessing the Effects of Auricular Acupressure on Newborns With NAS
|
N/A | |
| Completed |
NCT01958476 -
Improving Outcomes in Neonatal Abstinence Syndrome
|
Phase 3 | |
| Active, not recruiting |
NCT01734551 -
NAS Treatment - Opiate Versus Non-Opiate
|
Phase 4 | |
| Completed |
NCT00496951 -
Vagal Tone and Neonatal Abstinence Syndrome
|
N/A | |
| Completed |
NCT02851303 -
Morphine Versus Methadone for Opiate Exposed Infants With Neonatal Abstinence Syndrome
|
Phase 4 | |
| Recruiting |
NCT05226624 -
The Alberta Neonatal Abstinence Syndrome Mother-Baby Care ImprovEmeNT Program
|
N/A | |
| Completed |
NCT03670160 -
Clonidine Versus Phenobarbital as Adjunctive Therapy for Neonatal Abstinence Syndrome
|
Phase 2 | |
| Not yet recruiting |
NCT04611659 -
Averting NAS Among Opioid-Using Young Women Receiving MAT Using Buprenorphine
|
N/A | |
| Completed |
NCT01452789 -
Blinded Trial of Buprenorphine or Morphine in the Treatment of the Neonatal Abstinence Syndrome
|
Phase 3 | |
| Completed |
NCT04588519 -
tAN to Mitigate Withdrawal Behaviors in Neonates
|
N/A | |
| Completed |
NCT02797990 -
Conflict Between Maternal Autonomy and Child Health in Substance-use
|
N/A | |
| Completed |
NCT02801331 -
Efficacy and Outcomes of a Non-Pharmacological Intervention for Neonatal Abstinence Syndrome
|
N/A | |
| Terminated |
NCT03246243 -
Quantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High Risk
|
||
| Completed |
NCT03567603 -
Sound Processing Changes in Babies With Opioid Exposure
|
||
| Recruiting |
NCT06303986 -
Study to Collect Data for Neonatal Abstinence Syndrome (NAS) and Evaluate the Automated Data Collection Process
|
||
| Active, not recruiting |
NCT03725332 -
The PATH Home Trial: A Comparative Effectiveness Study of Peripartum Opioid Use Disorder in Rural Kentucky
|
N/A | |
| Recruiting |
NCT04983563 -
Actigraphy and Neonatal Abstinence Syndrome of Hospitalized Newborn in Intensive Care Units
|
N/A | |
| Completed |
NCT04298853 -
Optimal Morphine Dosing Schedule for Neonatal Abstinence Syndrome
|
Phase 4 | |
| Completed |
NCT02182973 -
Donor Human Milk in Neonatal Abstinence Syndrome
|