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White Spot Lesions clinical trials

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NCT ID: NCT05948228 Not yet recruiting - White Spot Lesions Clinical Trials

Prevention of White Spot Lesions Using Bioactive Gel

Start date: August 2023
Phase: Phase 1
Study type: Interventional

white spot lesions are a common problem and are reported in up to 96% of orthodontic patients. In this study, the preventive effect of bioactive gel is evaluated in comparison to fluoride.

NCT ID: NCT05733676 Recruiting - Clinical trials for Orthodontic Appliance Complication

Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment

Start date: May 30, 2023
Phase: N/A
Study type: Interventional

Dental cavities are among the most frequent diseases that affect teeth, particularly in patients who are treated with braces due to the difficulty in maintaining good oral hygiene in the presence of the mouth appliances. The white spot lesion (WSL) is the first clinical sign of cavities that presents itself as a milky-white opacity when located on the front face of the tooth. The aim to manage these early lesions focuses on promoting natural remineralization and preventing further demineralization. Various materials have been introduced for management of WSLs including MI paste and MI paste combined with fluoride (MI paste plus). Recently, a new material called resin infiltration has been found to treat these lesions with high esthetic results and great performance. According to the few numbers of in-vivo studies investigating the effectiveness of remineralization products, the aim of the current study is to clinically compare the outcome of the resin-infiltration and etching + MI paste plus to stop and improve the appearance of the WSL on front teeth in patients after treatment with braces.

NCT ID: NCT05562856 Completed - White Spot Lesions Clinical Trials

Clinical Evaluation of White Spot Lesions Treated by S-PRG Material and Composite Sealants in Comparison With ICON

Start date: January 20, 2020
Phase: N/A
Study type: Interventional

Dental caries is the primary cause of tooth loss and oral diseases. Dental decay is a continuous pathological process with loss of tooth minerals, demineralization, which involves the destruction of tooth structure from acids. The first sign of early active demineralization is white spot lesions (WSLs) on the tooth surface, meanwhile, subsurface active mineral decomposition.

NCT ID: NCT03990935 Not yet recruiting - White Spot Lesions Clinical Trials

Remineralization Potential of Ginger and Rosemary Herbals Versus Sodium Fluoride in Treatment of White Spot Lesions

Start date: July 2019
Phase: N/A
Study type: Interventional

To evaluate the effectiveness of ginger and rosemary herbals versus sodium fluoride in remineralization of incipient enamel caries.

NCT ID: NCT02912741 Not yet recruiting - White Spot Lesions Clinical Trials

One Year Clinical Evaluation of White Spot Lesions Treated With Newly Introduced Resin Modified Glass Ionomer in Comparison to Resin Infiltration in Anterior Teeth Split Mouth Technique

Start date: January 2017
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the addition of new technology of resin modified glass-ionomer in comparison to resin infiltration in treating post-orthodontic white spot lesions; both applies into the same patient's mouth; to reveal which material will have more clinical satisfactory performance inside the oral cavity and to overcome the high expensive cost in treating such clinical cases

NCT ID: NCT02341872 Completed - White Spot Lesions Clinical Trials

Compare the Efficacy of the Remineralization Agents on the White Enamel Lesions

Start date: August 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether Fluoride varnish + calcium (Clinpro White Varnish) and polipeptide solution (Curodont Repair) are effective in the treatment of remineralization therapy. The investigators will diagnose their alone or in combination effects on white spot lesions. Aesthetics (tooth-colored), remineralization, microbiological effects will be evaluated separately. Spectrophotometer (Vita Easy Shade) , Quantitative Light Fluorescence (QLF), Diagnodent(Cavo Diagnodent) and culture methods in microbiology laboratories are used for aesthetic, remineralization and microbiological assessments. The measurements will be made baseline, 6 weeks, 3 months and 6 months later after the applications and recorded.

NCT ID: NCT01881100 Completed - Caries Clinical Trials

Randomized Trial on Resin Infiltration in Deciduous Teeth

infiltration
Start date: January 2011
Phase: N/A
Study type: Interventional

It was hypothesized that resin infiltration in conjunction with fluoride varnish treatment of smooth-surface caries lesions in deciduous teeth reduce considerably the progression of treated caries lesions, compared to fluoride varnish therapy only.

NCT ID: NCT01500187 Completed - White Spot Lesions Clinical Trials

Fluoride Varnish for Treatment of White Spot Lesions

Start date: February 2012
Phase: N/A
Study type: Interventional

Study will look at ability of fluoride varnish to remineralize white spot enamel lesions that can occur around the edge of fixed orthodontic brackets.

NCT ID: NCT01344473 Completed - Clinical trials for Orthodontic Treatment

A Trial of Tooth Mousse to Remineralise Post-orthodontic Treatment White Spot Lesions

Start date: March 2011
Phase: N/A
Study type: Interventional

Fixed dental braces are associated with the risk of developing White Spot Lesions (WSLs), which appear as white chalky marks on the teeth. They develop as a result of the acid produced by bacteria in dental plaque dissolving the outer surface of the tooth, known as demineralisation. Recently, amorphous calcium phosphate (ACP) stabilised by casein phosphopeptide (CPP) has become available, and it is reported to help rebuild the surface of teeth which have WSLs. CPP-ACP is available incorporated into a crème known as Tooth Mousse (TM). While there appears to be sufficient evidence regarding the use of CPP-ACP in promoting general remineralisation, for the first time this study aims to examine the use of CPP-ACP to treat WSLs in post-orthodontic participants.