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Wegener's clinical trials

View clinical trials related to Wegener's.

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NCT ID: NCT01405807 Recruiting - Vasculitis Clinical Trials

Alemtuzumab for ANCA Associated Refractory Vasculitis

ALEVIATE
Start date: February 2011
Phase: Phase 4
Study type: Interventional

Overview: This open label, randomized, multi-centre study will enroll and treat 24 patients with refractory AAV. Aims: To determine the clinical response and severe adverse event rates associated with alemtuzumab therapy among patients with relapsing or refractory ANCA associated vasculitis (AAV). Hypothesis: Treatment with alemtuzumab induces sustained remission in AAV and will reduce immunosuppressive and steroid exposure.

NCT ID: NCT00315393 Completed - Clinical trials for Microscopic Polyangiitis

Longitudinal Protocol for Granulomatosis With Polyangiitis (Wegener's) and Microscopic Polyangiitis

Start date: April 2006
Phase:
Study type: Observational

Granulomatosis with polyangiitis (Wegener's) (GPA) and microscopic polyangiitis (MPA) are two rare immune system disorders that cause the inflammation of blood vessels, or vasculitis. In order to properly treat these diseases, it is critical that the level of disease activity can be determined over the course of the disease. The purpose of this study is to determine new biological markers, or biomarkers, that may be used to assess the severity of disease in people with GPA or MPA.