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Weaning clinical trials

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NCT ID: NCT05706441 Completed - COVID-19 Clinical Trials

Lung and Diaphragm Ultrasound Evaluation During Weaning From Mechanical Ventilation in COVID-19 Patients

Start date: January 11, 2023
Phase:
Study type: Observational

The goal of this observational study is to learn about the function of lung and diaphragm ultrasound during weaning from mechanical ventilation in COVID-19 patients. The aim of this study was that the lung ultrasound score and diaphragm muscle mobility could be a potential predictive factor of weaning success.

NCT ID: NCT05297357 Completed - Weaning Clinical Trials

Complementary Weaning With Adult Food Typical of the Mediterranean Diet

Start date: May 1, 2015
Phase: N/A
Study type: Interventional

A Randomized Controlled Clinical Trials was conducted to study the medium-long term impact of a complementary weaning using adult foods typical of Mediterranean Diets (MD) on children taste development and eating habits, and on the microbiota composition. Main objectives were to assess the effect of such weaning scheme on: 1. medium-long term adherence of the children to the MD (Primary aim). 2. familial eating habits to verify how many changes may come from an early education of the kid toward a Mediterranean eating style 3. the BMI of the children 4. gut microbiota composition

NCT ID: NCT03185962 Completed - Clinical trials for Mechanical Ventilation

Predictors Of Successful Extubation in Critically Ill Patients: Multicentre Observational Study

POSE
Start date: May 1, 2017
Phase:
Study type: Observational

Extubation failure can directly worsen patient outcomes. Therefore, the decision to extubate is a critical moment during an intensive care unit (ICU) stay. The decision to extubate is usually made after a weaning readiness test involving spontaneous breathing on a T-piece or low levels of ventilatory assistance. However, extubation failure still occurs in 10 to 20% of patients. The investigators focused on previously reported physiological risk factors, and were able to obtain from common clinical practice: 1) age, 2) underlying cardiovascular disease, 3) underlying respiratory disease or occurrence of pneumonia, 4) rapid shallow breathing index (RSBI), 5) positive fluid balance during the previous 24 hours, 6) the ratio of arterial oxygen partial pressure to fractional inspired oxygen, 7) Glasgow Coma Scale, 8) respiratory tract secretions. The investigators aimed to assess the incidence and risk factors for extubation failure among critically ill patients who passed the 30 min spontaneous breathing test (SBT) using a low level of pressure support (PS) with positive end-expiratory pressure (PEEP), in a prospective multicenter study.

NCT ID: NCT02723565 Completed - Clinical trials for Acute Respiratory Failure

Ultrasound to Evaluate Failure of Liberation From Mechanical Ventilation

USEFUL
Start date: April 2014
Phase:
Study type: Observational

This study will evaluate the heart, lungs and diaphragm of patients who fail a trial of spontaneous breathing to determine the physiological mechanism of weaning failure.

NCT ID: NCT01280773 Completed - Weaning Clinical Trials

Effect of NAVA on Weaning Duration in Difficult to Wean Patients

Start date: September 30, 2011
Phase: N/A
Study type: Interventional

It has been showed that over assist and patient ventilator asynchrony often occur in mechanical ventilated patients, especially in patients who failed weaning, which are associated with a prolonged duration of mechanical ventilation.Neurally adjusted ventilatory assist (NAVA) improves patient-ventilator synchrony, prevents excessive assist induced diaphragm inactivation. So the aim of this study was to detect that whether NAVA compared with PSV has the ability to reduce the duration of weaning in difficult to wean patients.

NCT ID: NCT00956540 Completed - Tracheostomy Clinical Trials

Does Deflating the Tracheal Cuff Shorten Weaning Time?

Start date: December 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether deflating the tracheal cuff in tracheostomized patients, during disconnections from ventilatory support along the weaning phase shortens the weaning time.

NCT ID: NCT00922493 Completed - Weaning Clinical Trials

Inspiratory Muscle Training in Weaning

IMT
Start date: December 2007
Phase: Phase 4
Study type: Interventional

Background: the objective of the present inquiry was to evaluate the weaning process in intubated older people subjected to inspiratory muscle training and to correlate the predictors of ventilatory interruption with its success. Methods: the patients were divided randomly into an experimental group (EG, n=14; age=82±4 years) that received conventional physiotherapy plus inspiratory muscle training (IMT) with threshold IMT® and a control group (CG, n=14; age=81±6 years) that received only conventional physiotherapy. The predictors evaluates were the maximum inspiratory pressure (MIP) and the index of Tobin (IT). The protocol for muscle training consisted of an initial load of 30% MIP, which was increased by 10% daily; training was administered for five minutes, twice a day, seven times a week with supplemental oxygen for the entire period from the decision to wean up to extubation.

NCT ID: NCT00910377 Completed - Breastfeeding Clinical Trials

Adolescent Mothers, Grandmothers, Breastfeeding and Complementary Feeding

Start date: May 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether counseling sessions on breastfeeding for adolescent mothers and their grandmothers in the maternity ward and at home are effective in to improve the exclusive and total breastfeeding rates during the first six month, as well as the convenient timing of supplementary feeding introduction.

NCT ID: NCT00858026 Completed - Weaning Clinical Trials

Impact of a Fermented Infant Formula in Weaning Babies

Start date: April 2006
Phase: N/A
Study type: Interventional

When mothers wanted to shift from breast milk to infant formulae, babies were randomly assigned to receive a fermented or a standard formula. Biological and clinical investigations were achieved at baseline (V1), and after one (V2) and three months (V3) of consumption of study formula. Intestinal microbiota was assessed by using culture-dependent techniques.

NCT ID: NCT00852891 Completed - Critical Care Clinical Trials

Cardiorespiratory Changes in Patients Being Weaned Off Mechanical Ventilation

Start date: December 2005
Phase: N/A
Study type: Observational

The objective of this study was to analyze changes in cardiac function using Doppler echocardiogram in critical patients during weaning from mechanical ventilation using two different weaning methods (pressure support and T-tube) and to compare a subgroup of patients: success vs. failure in weaning and patients with vs. without heart disease.