Weaning Failure Clinical Trial
Official title:
Critical Care Ultrasound Guided Weaning
Weaning patients from the ventilator in the intensive care unit is sometimes difficult because of three main interrelated etiologies: impaired lung, heart or diaphragm function. In this context, ultrasonography performed during tests for extubation of patients may enable the diagnosis of cardiac dysfunction, loss of pulmonary aeration, diaphragm dysfunction, and venous congestion, thereby reducing the number of failures in extubation. The combination of TTE (Trans Thoracic Echocardiography), LUS (Lung Ultrasound), DUS (Diaphragmatic ultrasound) and VEXUS (Venous excess Ultrasound) may enable the identification of the etiology of weaning failure and reduce the number of extubation failures by enabling the development of an appropriate treatment strategy. With this study, it is aimed to contribute to the literature in this sense.
The aim of this study is to reduce the number of extubation failures by defining the etiology of weaning failure and developing appropriate treatment strategies by using intensive care ultrasonography applications in combination (defining cardiac, pulmonary, diaphragmatic and venous congestion). Most patients can be extubated after the first SBT (spontaneous Breathing Trial). A patient who fails extubation is automatically classified as difficult weaning, and intensive care professionals frequently encounter patients who are difficult to wean from mechanical ventilation. Before performing a new SBT following a failed SBT, the cause of the failure should be determined and an appropriate treatment strategy developed. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT05539599 -
Comprehensive Ultrasound Evaluation as a Predictor of Weaning
|
||
Completed |
NCT02845076 -
Weaning From Noninvasive Ventilation
|
N/A | |
Completed |
NCT01915563 -
Rest After Spontaneous Breathing Trial for Prevention of Post-extubation Failure
|
N/A | |
Recruiting |
NCT01721434 -
Effects of Levosimendan on Diaphragm Function in Mechanically Ventilated Patients
|
Phase 2/Phase 3 | |
Completed |
NCT01928277 -
Weaning From Mechanical Ventilation: Spontaneous Breathing Trial and the Assessment of Work of Breathing
|
N/A | |
Recruiting |
NCT05632822 -
Value of Diaphragm Function Predicting Weaning From Mechanical Ventilation
|
||
Completed |
NCT06332768 -
NIV Versus HFO Versus Standard Therapy Immediately After Weaning From Mechanical Ventilation in ARDS Patients
|
N/A | |
Completed |
NCT03240263 -
Inspiratory Muscle Training in Difficult to Wean Patients
|
N/A | |
Completed |
NCT01867853 -
Volume Responsiveness Before SBT Predicts the Outcome of Mechanical Ventilation Weaning in Critically Ill Patients
|
N/A | |
Recruiting |
NCT06040138 -
Monitoring of Breathing Effort Through Pressure Time Product Measurement Using Airway Occlusion Pressure
|
||
Completed |
NCT06224010 -
Respiratory Drive and Inspiratory Effort in COVID-19 Associated ARDS
|
||
Completed |
NCT03129217 -
The Validity of Maximal Diaphragm Thickening Fraction to Measure Diaphragm Function in Mechanically Ventilated Patients
|
||
Not yet recruiting |
NCT05431036 -
Evaluation of a Combined Model in Predicting Weaning Outcome in Critically Ill Patients.
|
||
Completed |
NCT05550220 -
A Modified Cuff Leak Test and Reintubation in Mechanically Ventilated Patients
|
N/A | |
Recruiting |
NCT05906888 -
Weaning With Tracheostomy - an Observational Study on Patient-centered Outcomes
|
||
Recruiting |
NCT05944588 -
Predictive Value of Chest Ultrasound Observation on Extubation Failure
|
||
Not yet recruiting |
NCT05802745 -
P0.1 and Extubation Failure in Critically Ill Patients
|
||
Recruiting |
NCT03894189 -
The Effect of Doxapram Versus Theophylline on Diaphragmatic Function
|
N/A | |
Completed |
NCT01877850 -
Utility of a Weaning Protocol in ICU
|
N/A | |
Completed |
NCT03580720 -
Electromyography for Diaphragm Effort
|
N/A |