Clinical Trials Logo

Clinical Trial Summary

The main objective of the study is to examine the extent of agreement between patient and health care provider assessments of work of breathing and the association of agreement with demographic- and disease-related factors.


Clinical Trial Description

Mechanical ventilation is among the most common interventions in the intensive care unit (ICU). Over the last two decades, numerous studies have investigated methods to improve outcomes of patients receiving mechanical ventilation. Despite this proliferation of data, a large, multi-national cohort study found clinical outcomes such as duration of ventilation and ICU stay have not improved significantly between1998 to 2004.

It is recommended that weaning should be considered as early as possible in the patient trajectory and spontaneous breathing trials (SBT) attempted, as SBT are the best diagnostic criteria to determine extubation readiness. The decision of ready to extubate is considered complex because both delayed and failed extubations are associated with increased ventilator time and increased mortality. It is shown that dyspnea occurs among nearly half of ventilator patients and is strongly associated with anxiety and delayed extubation. Between 30-75% of ICU patients report anxiety where dyspnea, impaired communication skills, and sleep disturbances may be predisposing factors. The assessments of work of breathing and clinical deterioration are important sub-categories in clinical judgment for determining weaning tolerance.

There is little evidence whether the patients experiences of work of breathing is correlating with physicians and nurses. Hence, we suggest the need to evaluate the interobserver agreement for clinical assessment in weaning.

The main objective of the study is to examine the extent of agreement between patient and health care provider assessments of work of breathing and the association of agreement with demographic- and disease-related factors. ;


Study Design

Time Perspective: Prospective


Related Conditions & MeSH terms


NCT number NCT01928277
Study type Observational
Source University of Tromso
Contact
Status Completed
Phase N/A
Start date September 2012
Completion date December 2014

See also
  Status Clinical Trial Phase
Completed NCT05539599 - Comprehensive Ultrasound Evaluation as a Predictor of Weaning
Completed NCT02845076 - Weaning From Noninvasive Ventilation N/A
Completed NCT01915563 - Rest After Spontaneous Breathing Trial for Prevention of Post-extubation Failure N/A
Recruiting NCT01721434 - Effects of Levosimendan on Diaphragm Function in Mechanically Ventilated Patients Phase 2/Phase 3
Recruiting NCT05632822 - Value of Diaphragm Function Predicting Weaning From Mechanical Ventilation
Completed NCT06332768 - NIV Versus HFO Versus Standard Therapy Immediately After Weaning From Mechanical Ventilation in ARDS Patients N/A
Completed NCT03240263 - Inspiratory Muscle Training in Difficult to Wean Patients N/A
Completed NCT01867853 - Volume Responsiveness Before SBT Predicts the Outcome of Mechanical Ventilation Weaning in Critically Ill Patients N/A
Recruiting NCT06040138 - Monitoring of Breathing Effort Through Pressure Time Product Measurement Using Airway Occlusion Pressure
Completed NCT06224010 - Respiratory Drive and Inspiratory Effort in COVID-19 Associated ARDS
Completed NCT03129217 - The Validity of Maximal Diaphragm Thickening Fraction to Measure Diaphragm Function in Mechanically Ventilated Patients
Not yet recruiting NCT05431036 - Evaluation of a Combined Model in Predicting Weaning Outcome in Critically Ill Patients.
Completed NCT05550220 - A Modified Cuff Leak Test and Reintubation in Mechanically Ventilated Patients N/A
Recruiting NCT05906888 - Weaning With Tracheostomy - an Observational Study on Patient-centered Outcomes
Recruiting NCT05944588 - Predictive Value of Chest Ultrasound Observation on Extubation Failure
Not yet recruiting NCT05802745 - P0.1 and Extubation Failure in Critically Ill Patients
Recruiting NCT03894189 - The Effect of Doxapram Versus Theophylline on Diaphragmatic Function N/A
Completed NCT01877850 - Utility of a Weaning Protocol in ICU N/A
Completed NCT03580720 - Electromyography for Diaphragm Effort N/A
Recruiting NCT03880864 - Lung Ultrasound for Predicting Outcome of Weaning From Mechanical Ventilation Phase 1