Weaning Failure Clinical Trial
Official title:
Non Pharmacological Randomized Clinical Trial Designed to Evaluate the Difference of the Duration of Weaning Process From the Ventilator Between Protocol-driven Weaned Patients and Clinical-driven Weaned Patients.
The purpose of this study is to evaluate the difference of the duration of weaning process from the ventilator between protocol-driven weaned patients and clinical judgment driven weaned patients.
All patients with prolonged weaning and who required tracheostomy are enrolled in the study.
These patients are randomized as "Case or Control" by a computer program.
Patients can start the weaning process when the acute phase of the respiratory failure has
been resolved and pressure support ventilation was setted.
For all this patients are calculated modified-BWAP(BWAP-M) and TOBIN indexes. The "Case"
patients started the weaning protocol process only if BWAP-M value is more than 15 or BWAP-M
10-15 with Tobin index < 100.
If not, the BWAP-M and Tobin will be calculated every day. The Control patients will start
weaning by clinical judgement even if the BWAP-M value is less than 10.
For all patients are calculated: the duration of weaning process, the ICU length of stay and
the duration of the mechanical ventilation.
;
Observational Model: Case Control, Time Perspective: Prospective
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