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Warts clinical trials

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NCT ID: NCT05488860 Recruiting - Skin Diseases Clinical Trials

Piezoelectric Drived Microneedling in Treating Refractory Skin Diseases

Start date: July 30, 2022
Phase: N/A
Study type: Interventional

Piezoelectric drived microneedling treats refractory skin disorders using hollow microneedles assisted by ultrasound. Mechanically, the injection of medicine by hollow microneedling could makes the distribution of medicine more evenly. And the addition of ultrasound technique improves the effectiveness of microneedling. Investigators plan to conduct a pilot study to investigate the efficacy of using piezoelectric drived microneedles in treating refractory skin diseases.

NCT ID: NCT05429151 Recruiting - Clinical trials for Acyclovir and Candida Antigen in Treatment of Plantar Wart

Intralesional Injection of Acyclovir Versus Candida Antigen in Treatment of Plantar Warts

Start date: June 13, 2022
Phase: Phase 4
Study type: Interventional

This study aims to evaluate the efficacy of intralesional injection of acyclovir versus candida antigen in plantar wart patients will be randomly divided into 2 groups,At least 20 patients will be enrolled in each group. Group 1: will be treated with intralesional injection of acyclovir 250 mg acyclovir vial diluted with 3.5 ml saline to get approximately 70 mg/ml solution. The base of each wart was injected with 0.1 ml of intralesional acyclovir (70 mg/ml) every 2 weeks until the resolution of warts or for a maximum of 5 sessions Group 2: will be treated by intralesional Candida antigen injection (candida antigen ) at a dose of 0.2 mL. injected into the largest wart every 2 weeks until complete clearance of warts or for a maximum of 5 treatment sessions. 3.Patient evaluation: Assessment of treatment efficacy and side effects will be carried out by clinical examination and comparative photographic evaluation and dermoscopy

NCT ID: NCT05409365 Recruiting - Healthy Clinical Trials

Assessment of Squamous Cell Carcinoma antigen2 in Verruca Vulgaris

Start date: May 1, 2022
Phase:
Study type: Observational

This study aims to assess the expression of SCCA2 in the skin of patients with warts and to detect its correlation with characteristics of warts.

NCT ID: NCT05383625 Completed - Verruca Viral Clinical Trials

Gardasil Versus Cervarix in the Treatment of Warts

Start date: September 1, 2020
Phase: Phase 3
Study type: Interventional

Warts are common, benign, epidermal proliferations caused by HPV infecting skin and mucous membranes. Treatment of warts poses a true challenge despite existing variable therapeutic modalities, whether destructive or immunotherapeutic. Human papilloma virus (HPV) vaccines are FDA approved for the prevention of genital warts and wart related precancerous and cancerous lesions but they are not indicated for treatment of preexisting warts yet

NCT ID: NCT05371834 Active, not recruiting - Warts Clinical Trials

Microwave Treatment of Common and Plantar Warts

Start date: July 6, 2022
Phase: N/A
Study type: Interventional

This is a multi-center, open, randomized, parallel-group, controlled, blind-assessed trial of approximately 124 subjects that require treatment for up to 5 common or plantar warts. Subjects will be randomized to one of two treatment groups: Microwave Treatment (Swift® system) or Cryotherapy.

NCT ID: NCT05326152 Completed - Clinical trials for Intralesional Versus Intramuscular Hepatitis B Vaccine for Multiple Common Warts

Intralesional Versus Intramuscular Hepatitis B Vaccine Immunotherapy for Warts

Start date: November 25, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Assessment of the effectiveness of intralesional and intramuscular hepatitis B vaccine in treatment of multiple common warts.

NCT ID: NCT05324904 Not yet recruiting - Plantar Wart Clinical Trials

Intralesional Vitamin D3 Versus Intralesional Acyclovir in Treatment of Plantar Warts

Start date: October 2022
Phase: N/A
Study type: Interventional

To evaluate and compare the efficacy and safety of intralesional acyclovir versus intralesional vitamin D3 in the treatment of plantar warts

NCT ID: NCT05314127 Recruiting - Warts Flat Clinical Trials

Efficacy of Tazarotene in Treatment of Verruca Plana

Start date: April 15, 2022
Phase: Phase 2
Study type: Interventional

Verruca plana is a common skin infection with worldwide distribution. Approximately 10% of general population is infected with flat warts and it represents up to 18 % of the patients seeking treatment for warts. Verruca plana is not merely an infectious disease but also affects the quality of patients' life. Verruca plana causes major cosmetic and social concerns. Lesions' persistence and recurrence cause frustrations and psychological distress which motivate patients to seek different treatment strategies. Verruca plana commonly affects the school aged children which augments its effect on the psychological and social development of children with stigmatization and bullying are great risks. The available treatment strategies neither ensured complete clearance of the disease nor were free of side effects. Frequently used physical removal methods are operator dependent and commonly lead to irritation, local inflammation, scars, dyspigmentation, and disfigurement. In this study we evaluate the efficacy and the safety of tazarotene gel 0.1% in the treatment of verruca plana compared to imiquimod or 5-fluorouracil

NCT ID: NCT05300009 Not yet recruiting - Warts Clinical Trials

Efficacy and Safety of Topical Methotrexate Gel 1% Coupled With Microneedling in Treatment of Warts

Start date: June 15, 2022
Phase: N/A
Study type: Interventional

To study the clinical efficacy of the topically applied MTX hydrogel preparation combined with microneedling to increase drug delivery and efficacy in comparison with cryotherapy in treatment of warts.

NCT ID: NCT05291845 Recruiting - Clinical trials for Human Papilloma Virus

Candida Antigen and Bivalent HPV Vaccine in the Treatment of Multiple Warts

Start date: April 3, 2022
Phase: Phase 2
Study type: Interventional

To follow up the efficacy and safety of Candida antigen, bivalent HPV vaccine in treatment of common warts either mono or combined intralesional therapy