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Vomiting clinical trials

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NCT ID: NCT06282211 Recruiting - Nausea and Vomiting Clinical Trials

the Efficacy and Safety of Ondansetron Oral Soluble Pellicles

Start date: February 20, 2024
Phase: Phase 3
Study type: Interventional

The name of this prospective study is a multicenter, open-label, randomized controlled clinical study of the efficacy and safety of Ondansetron Oral Soluble Pellicles for the prevention of delayed nausea and vomiting induced by highly emetogenic chemotherapy.

NCT ID: NCT06268717 Recruiting - Clinical trials for Irritable Bowel Syndrome

GI Alpha-Gal Study

Start date: October 17, 2023
Phase: N/A
Study type: Interventional

This is a double-blind, crossover food challenge study using pork with and without α-gal in patients with a clinical diagnosis of gastrointestinal (GI)- α-gal allergy, and to investigate the pathophysiology underlying their symptoms.

NCT ID: NCT06266819 Recruiting - Clinical trials for Hyperemesis Gravidarum

The Effect of Mint Flavored Chewing Gum on Hyperemesis Gravidarum Nausea Vomiting Severity, Coping With Stress and Anxiety Level in Pregnants With Hyperemesis Gravidarum

Start date: January 15, 2024
Phase: N/A
Study type: Interventional

In the research planned as a randomized controlled study, the experimental groups will be administered routine hyperemesis gravidarum (HG) treatment as well as chewing mint-flavored gum, while the control group will only receive routine HG treatment and no intervention will be performed. This study aims to contribute to the literature by investigating the effect of chewing mint-flavored gum on the severity of nausea and vomiting, coping with stress, and anxiety levels due to hyperemesis gravidarum in pregnant women.

NCT ID: NCT06254131 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

Preoperative Ondansetron Lozenge for Prevention of Postoperative Nausea and Vomiting in Caesarean Section

Start date: February 10, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to estimate the effect of preoperative ondansetron lozenge on prevention of postoperative nausea and vomiting in caesarean section.

NCT ID: NCT06246240 Recruiting - Clinical trials for Pregnancy Nausea and Vomiting

Vitamin C Chewing Gum, Pregnancy Nausea and Vomiting

PregnancyNause
Start date: October 8, 2023
Phase: N/A
Study type: Interventional

Although there are studies in the literature examining the effects of chewing gum or using vitamin C on nausea and vomiting symptoms, no study has been found examining the effect of vitamin C gum on the severity of nausea and vomiting during pregnancy. This study aimed to investigate the effect of vitamin C gum on the severity of pregnancy nausea and vomiting.

NCT ID: NCT06241547 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

PONV Prevention Via Percutaneous Nerve Electrical Stimulation on PC6

Start date: January 12, 2024
Phase: Phase 2
Study type: Interventional

This study aims to certify the effectiveness of percutaneous electrical nerve stimulation at Pericardium 6 (PC6) via a wearable equipment during perioperative period on preventing postoperative nausea and vomiting.

NCT ID: NCT06208917 Recruiting - Clinical trials for Pediatric Solid Tumor, Unspecified, Protocol Specific

Ondansetron (ODF) Versus Ondansetron Intravenously for the Prevention of Chemotherapy-induced Nausea and Vomiting Compare in Children

Start date: July 9, 2023
Phase: Phase 3
Study type: Interventional

The purpose is to evaluate the efficacy of ondansetron oral soluble film plus dexamethasone in preventing chemotherapy-induced nausea and vomiting (CINV) with MEC/HEC chemotherapy in children with solid tumor.

NCT ID: NCT06200168 Recruiting - Nausea and Vomiting Clinical Trials

Electroacupuncture for the Prevention of Chemotherapy-induced Nausea and Vomiting in Patients With Breast Cancer

Start date: December 20, 2023
Phase: Phase 3
Study type: Interventional

This randomized controlled phase III trial aims to evaluate the use of electroacupuncture in combination with olanzapine-containing standard quadruple antiemetic drugs for the treatment of nausea and vomiting induced by highly emetogenic chemotherapy (HEC) in patients with breast cancer. Furthermore, it will analyze the relationship between single nucleotide polymorphism and electroacupuncture treatment for chemotherapy-induced nausea and vomiting.

NCT ID: NCT06186141 Recruiting - Clinical trials for Patient-Controlled Analgesia

Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone

POPCORN
Start date: March 13, 2024
Phase: Phase 4
Study type: Interventional

POPCORN trial will compare the side effects and effectiveness of Morphine versus Oxycodone medication when prescribed for use as patient controlled analgesia (PCA) for pain relief for paediatric patients after-surgery. This trial is embedded into routine patient care using the hospital electronic medical record (EMR). Participants will be randomly assigned to either medication after they enrol in the study. The main questions the POPCORN trial aims to answer are: - 1. Is there a difference in the usage of medication to treat nausea and vomiting for those who received oxycodone PCA versus morphine PCA for post-surgery pain relief? - 2. Is there a difference in side effects or pain relief needed between the two groups? Study activities are as follows: - Participants enrolled to study during their pre-operative consultation - Participants are randomly assigned to morphine or oxycodone - No further study-specific activities expected from participant after enrolment and randomisation - Participant receives routine medical care as planned - Clinicians record assessments as per routine care in electronic medical record (EMR) - EMR data are extracted as trial data

NCT ID: NCT06170476 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in PONV

Start date: November 10, 2023
Phase: N/A
Study type: Interventional

This is a multicenter, randomized, double-blind, placebo-controlled Dose-Finding study. About 200 subjects undergoing elective laparoscopic abdominal or gynecological surgery are planned to be enrolled and randomized into four groups by a ratio of 1:1:1:1.