Volunteers Clinical Trial
Official title:
Effects of Mode of Contraction on Neuromuscular Fatigue in Young People Aged 18 to 35, Aged 60 to 80 and Very Old People Aged Over 80
Aging is associated with multiple deteriorations of the neuromuscular system. Given the increase in life expectancy, the investigators can now distinguish old adults (>60 years old) who conserve their neuromuscular capacities with regular physical activity and very old adults (>80 years old) who suffer from an inexorable decline, even if the number of octogenarians and their quality of life are progressively increasing. However, the most part of the literature on fatigue and neuromuscular capacity with aging focused on isometric tasks. The results showed a significant decrease in maximal force production capacity and a greater resistance to fatigue for old people compared to the young population. When fatigue is induced trough dynamic contractions, greater fatigability was observed in old adults compared to young adults. Investigations performed on the population aged over 80 years old are rare, showing greater fatigability in octogenarians than old men (aged 60-80 years old) during isometric tasks. The knowledge about the effects of dynamic contractions in this population are limited, and performed uniquely in single leg isokinetic mode. Evaluations that require the use of both legs and higher muscle mass involved in the task (cycloergometer) are needed. Understanding neuromuscular fatigue and fatigability across different exercise modalities is necessary to set adapted physical activity programs aimed to maintain autonomy in older individuals.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02922933 -
A Study to Examine the Effect of Omeprazole, Famotidine, and an Acidic Beverage on the Pharmacokinetics of Entinostat in Healthy Adult Subjects
|
Phase 1 | |
| Completed |
NCT02949999 -
Voclosporin in Healthy Japanese Volunteers
|
Phase 1 | |
| Completed |
NCT02922946 -
Study to Determine the Effect of the Timing of a Meal on the Pharmacokinetics of Entinostat
|
Phase 1 | |
| Recruiting |
NCT04038775 -
Take 2 Pills and Go Volunteer in the Morning
|
N/A | |
| Completed |
NCT01974037 -
Capsaicin on Salty Gustatory Cortices
|
Phase 4 | |
| Recruiting |
NCT04040608 -
Influence of Screen Sizes on Responses to Visual Analog Scales of Stress
|
||
| Completed |
NCT05789745 -
A Study to Evaluate Plasma Gelsolin in Healthy Volunteers
|
Phase 1 | |
| Completed |
NCT03453450 -
Exploring Volunteers' Experiences in Health TAPESTRY
|
||
| Terminated |
NCT01121380 -
A Study Intended to Evaluate Safety, Tolerability and Pharmacokinetics (PK) Parameters of BL-1021
|
Phase 1 | |
| Completed |
NCT05901662 -
Older Volunteers' Competence Training
|
N/A | |
| Terminated |
NCT02889042 -
Repeated Voluntary Drug Intoxication (IMVr): Characterization of a New Addictive Behavior by Clinical Phenotyping and Functional Imaging
|
N/A | |
| Recruiting |
NCT04256330 -
Cardiometabolic Health and Inflammatory Resolution
|
||
| Completed |
NCT05760963 -
Which Approach to Favor for Ultrasound-guided Lumbar Plexus Block (BPLE). Comparative Study.
|
||
| Completed |
NCT03289559 -
Effects of Testosterone and Fat Utilization
|
N/A | |
| Enrolling by invitation |
NCT04643444 -
Police COVID-19 Serosurvey
|
||
| Completed |
NCT02091271 -
Screening Protocol to Evaluate Volunteers for NIA Approved Studies
|
||
| Completed |
NCT02622867 -
Lactobacillus Plantarum 3547 Effects Over Inflammatory and Immunologic Markers
|
Phase 4 | |
| Completed |
NCT02942667 -
Magnetic Resonance Imaging of Human Biometrics
|
N/A | |
| Terminated |
NCT01573988 -
Satiety, Meal Frequency and Nutritional Aspects
|
N/A |