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Vitreous Detachment clinical trials

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NCT ID: NCT05249413 Completed - Cataract Clinical Trials

Early Vitrectomy for Endophthalmitis After Cataract Surgery

Start date: January 2, 2015
Phase:
Study type: Observational

Post-operative infectious endophthalmitis is devastating condition that causes a diffuse intraocular inflammation and may lead to blindness. Acute post-operative endophthalmitis usually presented within 6 weeks of intraocular procedure and diagnosis is confirmed by clinical examination and by the aid of B-scan ultrasonography.

NCT ID: NCT04865991 Completed - Vitreous Detachment Clinical Trials

Comparison of Propofol Target Controlled Infusion (TCI) and Sevoflurane

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

This study was an experimental, single-blinded, randomized controlled trial that aimed to compare recovery time between TCI propofol and sevoflurane. After ethical approval from Research Ethical Committee Faculty of Medicine, Universitas Indonesia (879/UN2.F1/ETIK/2017) and informed consent, patients aged 18-65 years old, body mass index 18 - 30 kg/m2, American Society of Anesthesiologists (ASA) status I-II who were scheduled for vitrectomy surgery under general anesthesia, at Kirana's Eye Operating Theatre Cipto Mangunkusumo National Referral Hospital from September until December 2017, were recruited in this study. All subjects would be recruited with a consecutive sampling method and randomly assigned into two groups, the TCI propofol group and sevoflurane group. Block random allocation was done for all subjects by using the random allocator program Winpepi.

NCT ID: NCT02897583 Completed - Clinical trials for Posterior Vitreous Detachment

YAG Vitreolysis for Floaters

Start date: February 2015
Phase: N/A
Study type: Interventional

This is a single-center, prospective randomized controlled trial evaluating the safety and efficacy of YAG vitreolysis versus sham for symptomatic Weiss ring due to posterior vitreous detachment.

NCT ID: NCT02435862 Completed - Clinical trials for Non-Proliferative Diabetic Retinopathy

A Clinical Trial Designed to Evaluate the Safety and Efficacy Study of Luminate® in Inducing PVD (Posterior Vitreous Detachment) in Non-Proliferative Diabetic Retinopathy

Start date: February 1, 2015
Phase: Phase 2
Study type: Interventional

A Phase 2, Randomized, Double-masked, Placebo-controlled Multicenter Clinical Trial Designed to Evaluate the Safety and Efficacy of Luminate in Inducing PVD in Subjects with Non-Proliferative Diabetic Retinopathy.

NCT ID: NCT01970267 Completed - Clinical trials for Posterior Vitreous Detachment

Clear Vision Study

Start date: October 2013
Phase: N/A
Study type: Interventional

Vitreous floaters are tiny, cloudy, clumps of cells that appear in the otherwise clear fluid (vitreous) that fills the back 3/4 of the eye. Floaters are commonly caused by eye conditions such as posterior vitreous detachment (PVD), vitreous syneresis and asteroid hyalosis. While these symptoms are considered physiological in nature, they can be of considerable inconvenience to many patients which affect essential activities. The investigators wish to assess the safety and efficacy of floater treatment in patients with highly symptomatic floaters using an FDA approved nanosecond infrared yttrium aluminum garnet (YAG) lasers.

NCT ID: NCT01415037 Completed - Clinical trials for Diabetic Retinopathy

Annular Array Ultrasound in Ophthalmology

Start date: October 2011
Phase:
Study type: Observational

The objective of this research is to improve the care of ocular disease and disorders, in particular the changes in the eye associated with diabetes, by providing clinicians with dramatically improved ultrasonic images of the entire eye. The research combines advanced high-frequency, high-resolution ultrasonic annular arrays transducers with new processing techniques designed to overcome several limits that have been reached with conventional high frequency ultrasound systems. The investigators propose that diagnosis of eye diseases using annular arrays can be more effective than the conventional ultrasound images by at least 50%; i.e., that for every 2 posterior vitreous detachments detected conventionally, 3 will be detected with the annular arrays.

NCT ID: NCT00831350 Completed - Clinical trials for Retinal Vein Occlusion

Posterior Vitreous Detachment (PVD) Assessment During Dual Retinal Vein Occlusion (RVO) Lucentis Evaluations

PADDLE
Start date: April 2009
Phase: Phase 2
Study type: Interventional

This is a study of subjects with retinal vein occlusion (RVO) specifically looking at the difference in outcomes between patients with posterior vitreous detachment (PVD) and those without PVD. Posterior vitreous detachment is a condition where the gel-like substance that occupies the space between the retina and the lens of the eye liquefies and separates from the retina. 20 subjects from Barnes Retina Institute will be enrolled in this study. Based on a pre-treatment ultrasound (a test utilizing high-frequency sound waves to look at the inside of the eye), high resolution OCT (a noninvasive procedure called optical coherence tomography to check the thickness of your retina) and clinical exam, subjects will be assigned to one of 2 groups at baseline: Group 1 will be those with PVD and Group 2 will be those without PVD. Then subjects will receive monthly intravitreal (inside the eye) injections of Ranibizumab.

NCT ID: NCT00633854 Completed - Clinical trials for Posterior Vitreous Detachment

High-frequency-ultrasound Annular Arrays for Ophthalmic Imaging

Start date: February 2008
Phase:
Study type: Observational

The objective of this research is to improve the care of ocular disease and disorders, in particular the changes in the eye associated with diabetes, by providing clinicians with dramatically improved ultrasonic images of the entire eye. The research combines advanced high-frequency, high-resolution ultrasonic annular arrays transducers with new processing techniques designed to overcome several limits that have been reached with conventional high-frequency ultrasound systems. We propose that diagnosis of eye diseases using annular arrays can be more effective than the conventional ultrasound images by at least 50%; i.e., that for every 2 posterior vitreous detachments detected conventionally, 3 will be detected with the annular arrays.

NCT ID: NCT00408720 Completed - Epiretinal Membrane Clinical Trials

Comparison of a Spectral OCT/SLO With the Stratus OCT for Imaging Various Retinal Pathologies

Start date: October 2006
Phase: N/A
Study type: Observational

The purpose of this study is to compare the newly released Spectral OCT/SLO (OTI, Toronto, Canada) with the Zeiss Stratus OCT (Carl-Zeiss Meditec, Dublin, CA) with regards to the quality of the images obtained as well as the ease of use.

NCT ID: NCT00198471 Completed - Clinical trials for Diabetic Retinopathy

Assessment of Intravitreous Injections of Vitrase for Inducing Posterior Vitreous Detachment

Start date: July 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy of intravitreous injections of Vitrase to induce posterior vitreous detachment(PVD) in subjects with moderate to severe non-proliferative diabetic retinopathy.