Clinical Trials Logo

Vitrectomy clinical trials

View clinical trials related to Vitrectomy.

Filter by:

NCT ID: NCT01255293 Completed - Clinical trials for Diabetic Retinopathy

Comparative Study of 1000 Centistoke Versus 5000 Centistoke Silicone Oil for Repair of Complex Retinal Detachments

Start date: November 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the retinal redetachment rates with 1000 centistoke versus 5000 centistoke silicone oil tamponade for repair of complex retinal detachments.

NCT ID: NCT01229410 Completed - Vitrectomy Clinical Trials

Pharmacokinetics of the Brimonidine Tartrate Posterior Segment Delivery System in Patients Undergoing Pars Plana Vitrectomy

Start date: December 2010
Phase: Phase 1
Study type: Interventional

This study will evaluate the pharmacokinetics of brimonidine following a single intravitreal administration of the 200 ug or 400 ug Brimonidine Tartrate Posterior Segment Drug Delivery System in patients 2, 4 or 8 weeks prior to undergoing a pars plana vitrectomy.

NCT ID: NCT01176331 Completed - Vitrectomy Clinical Trials

Outcomes of 20 and 23-gauge Combined Transconjunctival Pars Plana Vitrectomy

Start date: n/a
Phase: Phase 4
Study type: Observational

In a retrospective study, a combined 20 and 23-gauge pars plana vitrectomy procedure was performed in 21 eyes for various indications and proposed as a transition procedure to 23-gauge transconjunctival vitrectomy. Through use of combination of procedures postoperative complications, surgical trauma and healing time was decreased; operating time was reduced; costs were decreased.

NCT ID: NCT01159665 Completed - Vitrectomy Clinical Trials

The Purpose of This Study is to Evaluate the Pharmacokinetic Properties of Intravitreal Ocriplasmin Prior to Planned Primary Pars Plana Vitrectomy (PPV)

MIVI-10
Start date: July 2010
Phase: Phase 2
Study type: Interventional

To evaluate the pharmacokinetic properties of intravitreal ocriplasmin 125 µg dose when administered at different time-points prior to planned primary pars plana vitrectomy (PPV)

NCT ID: NCT01051648 Completed - Cataract Clinical Trials

Triamcinolone Assisted Anterior Vitrectomy

Start date: December 2007
Phase: Phase 2
Study type: Interventional

Injecting Triamcinolone acetenoide for visualizing and removing vitreous from the anterior chamber.

NCT ID: NCT00986362 Completed - Vitrectomy Clinical Trials

Clinical Trial of Intravitreal Microplasmin in Infants and Children Scheduled for Vitrectomy

MIC
Start date: February 2010
Phase: Phase 2
Study type: Interventional

To evaluate the safety and preliminary efficacy of intravitreal microplasmin as an adjunct to conventional vitrectomy for the treatment of pediatric patients.

NCT ID: NCT00927628 Completed - Vitrectomy Clinical Trials

Macular Hole Reopening

Start date: October 1990
Phase: N/A
Study type: Observational

The purpose of this investigation was to determine the incidence and the factors that cause a reopening of a macular hole (MH) after a surgical closure.

NCT ID: NCT00799227 Completed - Clinical trials for Diabetic Macular Edema

Safety and Efficacy of a New Treatment in Vitrectomized Subjects With Diabetic Macular Edema

Start date: January 1, 2009
Phase: Phase 2
Study type: Interventional

The study will evaluate the safety and efficacy of the intravitreal dexamethasone implant in the study eye of vitrectomized subjects with diabetic macular edema. Subjects will be followed for 26 weeks.

NCT ID: NCT00737022 Completed - Clinical trials for Proliferative Diabetic Retinopathy

Macular Appearance After Diabetic Vitrectomy

Start date: May 2005
Phase: N/A
Study type: Observational

Vitrectomy is one of the major treatment methods for complications of diabetic retinopathy. As surgical techniques and instruments improve, high anatomical success may be achieved; however, functional results are less favorable. Despite attached retina, postoperative visual function may be affected by various macular and disc abnormalities. Major changes include optic atrophy, atrophic retina, poor macular perfusion, and structural alternations of the macula. Funduscopy, fluorescein angiography, and, more recently, optical coherence tomography (OCT) can be used to detect and document these alterations. Although fluorescein angiography is valuable in the assessment of various macular lesions as well as retinal vascular abnormalities, its usefulness in evaluating macular changes is limited in eyes that have undergone diabetic vitrectomy. The quality of the images may be compromised by mild diffuse hyperfluorescence in the posterior pole in middle and late phase angiography, which obscures capillary detail and subtle macular changes. Furthermore, quantification of changes may not be possible. Recently, optical coherence tomography has become very useful for the detection of vitreomacular abnormalities. The examination is noninvasive, can qualify the changes and detect subtle abnormalities not evident with other imaging studies. In this study, OCT was applied to investigate how common macular structure abnormalities are present after surgery for complications of diabetic retinopathy, and how they may affect visual prognosis.

NCT ID: NCT00685490 Completed - Vitrectomy Clinical Trials

Vitrectomy for Branch Retinal Vein Occlusion

Start date: July 1995
Phase: N/A
Study type: Observational

To evaluate the long term outcomes of pars plana vitrectomy (PPV), with and without internal limiting membrane (ILM) peeling, in eyes with persistent macular edema secondary to branch retinal vein occlusion (BRVO). Results suggest the following hypothesis: - PPV, with and without ILM peeling, appears to be beneficial in eyes with persistent macular edema due to BRVO - Effectiveness is maintained long term - ILM peeling does not significantly affect postoperative best corrected visual acuity (BCVA)