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Vitamin D3 Deficiency clinical trials

View clinical trials related to Vitamin D3 Deficiency.

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NCT ID: NCT06142136 Completed - Clinical trials for Vitamin D3 Deficiency

The Effect of Vitamin D Sublingual Spray on Vitamin D3 Levels in the Blood Compared to Other Forms of Vitamin D3

Start date: March 28, 2021
Phase: N/A
Study type: Interventional

The randomized comparative study was performed on 99 outpatients with below 30 ng/ml of vitamin D. Participants were randomized into three groups to receive vitamin D3 supplementation in three different forms - sublingual spray, oral oil droplets, and capsules. Each participant received vitamin D3 4000 IU daily for 30 days and the vitamin D levels were measured before and after the intervention.

NCT ID: NCT04841213 Completed - Tooth Loss Clinical Trials

Dental Implants Rehabilitation in Patients With Vitamin D3 Imbalance

Start date: April 10, 2021
Phase: N/A
Study type: Interventional

Interventional retrospective prospective randomized clinical trial (RCT) in parallel groups. The sample size is 384 patients with loss of teeth and vitamin D imbalance. All patients will undergo or underwent dental implantation after additional investigations which reveal vitamin D imbalance (<30 ng/ml or <75 nmol/l). The 1 group will include 192 patients who will be or were operated on with dental implants after stabilization of vitamin D level with a help of an endocrinologist. The 2 group will include 192 patients who will be or were operated on during the treatment of vitamin D imbalance prescribed by the endocrinologist. The possible difference between groups can be considered the change of dental implants survival time and bone resorption level depending on the level of vitamin D and treatment time by the endocrinologist.

NCT ID: NCT03890458 Completed - Infertility Clinical Trials

The Effect of Vitamin D on Fertility

Start date: May 1, 2017
Phase: Phase 4
Study type: Interventional

Objective: To examine the effect of vitamin D supplements on the pregnancy and clinical pregnancy rate in embryo transfer cycles. Design: Experimental study with a pre- and post-test. Setting: In Vitro Fertilization Center Patients: Its sample consisted of 118 women, 58 in the experimental group and 60 in the control group. Intervention(s): At the beginning of the infertility treatment, the experimental group took vitamin D supplements, and the control group did not. Vitamin D supplementation for infertile women includes regulation of a diet rich in vitamin D, educational and motivational interviews about insolation, and taking vitamin D orally. Main Outcome Measure(s): 25(OH)D and beta HCG levels

NCT ID: NCT03499327 Completed - Clinical trials for Vitamin D3 Deficiency

Human Intervention Study to Increase 25-hydroxyvitamin D Levels

WeKo
Start date: March 5, 2018
Phase: N/A
Study type: Interventional

The interventional study will evaluate effectiveness and potential of a regularly consumption of wheat germ oil (UV treated) vs. wheat germ oil (UV untreated) to increase plasma vitamin D levels ín humans.

NCT ID: NCT03417700 Completed - Clinical trials for Vitamin D3 Deficiency

Vitamin D as a Factor Modifying Adaptation to Exercise

Start date: January 5, 2018
Phase: N/A
Study type: Interventional

Physical activity is a recommended, indispensable element of a healthy lifestyle as well as a countermeasure against many diseases often accompanied by the acute or chronic low grade inflammation. Papers published in recent years have demonstrated the anti-inflammatory effect of exercise. Based on current knowledge of the topic, own experience and preliminary work, it is expected the proposed research to provide information on the mechanism either determining or limiting pro-healthy effects of exercise in different age groups of people. Three different training programmes will be investigated. Specific goals of the project include the following: 1. Establish, whether regular Nordic Walking training and HIIT can reduce the low-grade systemic inflammation and which type of training is the most effective at doing so. 2. Establish, whether regular training can prevent muscle sarcopenia and assess if those changes are related to the concentration of the autophagy-inducing stress protein, HMGB1. 3. Establish, whether regular Nordic Walking training alters iron metabolism and evaluate its correlation with the inflammatory markers and bone-morphogenesis. 4. Establish, whether muscle-released irisin signals growth in the BDNF concentration in response to exercise and if these changes improve cognitive function. 5. Establish, whether Nordic Walking or HIIT training effectively improve the blood lipid profile and aerobic capacity, and if these effects correlate with the blood 25-OHD concentration. 6. Establish, whether concentration of vitamin D alters adaptation to training and modifies immunological response to regular training process.

NCT ID: NCT02178488 Completed - Clinical trials for Vitamin D3 Deficiency

Efficacy Study of Vitamin D Supplementation to Meticillin Resistant Staphylococcus Aureus (MRSA) Carriers

D-STAPH
Start date: December 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to treat persistent MRSA carriers with vitamin D supplementation during a 12 month to see if the number of MRSA positive patients can be reduced.

NCT ID: NCT01932788 Completed - Clinical trials for Vitamin D3 Deficiency

Preventing Health Disparities During Pregnancy Through Vitamin D Supplementation

Start date: January 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to give all mothers the best chance for a healthy pregnancy through vitamin D supplementation. We will study women of diverse racial/ethnic backgrounds who will receive either the current vitamin D standard of 400 IU/day (in the prenatal vitamin) or 4000 IU/day (dose found in previous pregnancy studies to achieve vitamin D sufficiency). This research is sponsored by the W.K. Kellogg Foundation and the Medical University of South Carolina. The purpose of this study is to examine the effectiveness and infection-fighting properties of the body in relationship to vitamin D levels. This study is being done at the Medical University of South Carolina (MUSC) clinics, and will involve approximately 450 volunteers.