Visual Impairment Clinical Trial
Official title:
Treatment of Infantile and Juvenile Patients With Bardet-Biedl-Syndrome With Metformin. Evaluation of a Visual Improvement as a Side Effect of the Pediatric Treatment of Adipositas - a Prospective Pilot Study Without Control
In this prospective pilot study without control group children and young adults (10-25 years old) diagnosed with Bardet-Biedl syndrome and treated with Metformin for their adipositas will be evaluated for a possible additional effect of Metformin on visual acuity.
Within experiments with animals a positive effect of Metformin concerning the photo receptors
was shown. Several patients of the university hospital Tübingen with Bardet-Biedl-Syndrome
and Metformin therapy due to their adipositas reported a subjective improvement of the visual
acuity which was confirmed by opthalmologic tests.
This will be checked in a prospective pilot study without control group including children
and young adults (10-25 years old) diagnosed with Bardet-Biedl syndrome and treated with
Metformin for their adipositas. Therefore a possible additional effect of Metformin on visual
acuity will be evaluated under controlled conditions.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06000865 -
Glaucoma Rehabilitation With Action viDeo Games and Exercise - GRADE
|
N/A | |
| Recruiting |
NCT05619432 -
Re:Garde Program - Training and Maintaining Visual Perception in Older Adults
|
N/A | |
| Completed |
NCT03670303 -
Trial of an Educational Intervention to Promote Spectacle Use Among Secondary School Children in Islamabad, Pakistan
|
N/A | |
| Completed |
NCT02896738 -
MRI Screening for Auditory Pathway Malformations in Visually Impaired Children
|
||
| Completed |
NCT01822717 -
Nonvisual Foot Inspection for People With Visual Imapirment
|
N/A | |
| Completed |
NCT03865134 -
Evaluation of Visual - Motor Development in Children With Retinopathy of Prematurity
|
||
| Active, not recruiting |
NCT04198350 -
Pancreatic Islet Transplantation to the Anterior Chamber of the Eye
|
N/A | |
| Recruiting |
NCT05220449 -
Re-Orchestration of Interregional Oscillatory Activity to Promote Visual Recovery
|
N/A | |
| Completed |
NCT04190147 -
Eye and Growth in Adolescents Born Moderate-to-late Preterm
|
||
| Completed |
NCT05135195 -
A Virtual Reality Platform Simulating Visual Impairment for Testing of Electronic Travel Aids and Performing Orientation and Mobility Training
|
N/A | |
| Recruiting |
NCT05199363 -
Pediatric Patient Experience on a Diagnostic Path
|
N/A | |
| Active, not recruiting |
NCT03767803 -
Collection of Whole Blood Samples for the Evaluation of Preeclampsia (Pre-E) Biomarkers From Pregnant Women
|
||
| Recruiting |
NCT03571217 -
Shanghai Beixinjing Diabetic Eyes Study
|
||
| Not yet recruiting |
NCT03726606 -
A Comparison of the Visual Performance of Trifocal Versus Extended Depth of Focus Intraocular Lenses
|
N/A | |
| Completed |
NCT02259088 -
A 12-month, Randomized, Efficacy and Safety Study of 0.5 mg Ranibizumab vs Laser in Chinese Diabetic Macular Edema (DME) Patients
|
Phase 3 | |
| Completed |
NCT06197607 -
Effect of Hand Exercises on Hand Grip Strength and Manual Ability in Children With Visual Impairment
|
N/A | |
| Withdrawn |
NCT04579653 -
Pupillometry and Locus Coeruleus Activation (PuLCA)
|
N/A | |
| Recruiting |
NCT05844982 -
Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy
|
Phase 3 | |
| Recruiting |
NCT02258113 -
Measuring of Neuro-visual Functionality With Ocusweep
|
N/A | |
| Completed |
NCT02607384 -
The Baltimore Reading and Eye Disease Study
|
N/A |