Osteoporotic Vertebral Fractures & Exercise

Status Recruiting

Clinical Trial Summary

Physiotherapy has an important place in the treatment of osteoporotic vertebral fractures. Therapeutic exercise is often recommended for patients with vertebral fractures to reduce pain and restore functional movement. There is not enough evidence in the literature to determine the effects of long-term exercise on osteoporotic fractures and their side effects. Therefore, the aim of this study is to evaluate the effectiveness of 12-week exercise training in patients with osteoporotic vertebral fractures.

Clinical Trial Description

Osteoporotic vertebral fractures are associated with increased morbidity (eg, pain, poor quality of life) and mortality. Therapeutic exercise is a conservative non-pharmacological treatment that is often recommended for patients with vertebral fractures to reduce pain and restore functional movement. There are preliminary studies showing that exercise may have an important role in improving quality of life and reducing the risk of re-fracture in these individuals. There are several reports of pain relief after short-term (6-10 weeks) exercise programs in people with spinal fractures, suggesting that there is uncertainty in the effects reported after longer-term (12-24 weeks) exercise. Data are scarce and there are only four studies examining this question, and one is a multi-component physical therapy intervention that includes exercise. Not all studies have examined individuals with severe pain at baseline. The quality assessment of the evidence for the effects of exercise on pain is very low. There is insufficient evidence in the literature to determine the effects of exercise on osteoporotic fractures and their side effects. Therefore, the aim of the study is to evaluate the effectiveness of 12-week resistance and balance exercises in patients with osteoporotic vertebral fractures.The group of patients who will exercise will be compared with individuals who do not receive any treatment or exercise. It is aimed to reveal the effects of exercise on pain, physical performance, quality of life, depression, loss of function, kinesiophobia and sleep quality. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05521724
Study type	Interventional
Source	Hasan Kalyoncu University
Contact	YASEMIN SALKIN
Phone	0505 116 53 13
Email	yaseminsalkin@mersin.edu.tr
Status	Recruiting
Phase	N/A
Start date	August 20, 2022
Completion date	December 1, 2022

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT06367582` - SPINE BONE CEMENTS OUTCOMES
Terminated	`NCT00748631` - Treatment of Malignant Vertebral Fractures With Percutaneous Balloon Kyphoplasty.	N/A
Completed	`NCT00463905` - Evaluation of the Impact of a Case-finding Strategy for Vertebral Fractures	N/A
Completed	`NCT03885466` - Nordic Walking for Individuals With Osteoporosis, Vertebral Fracture or Hyperkyphosis	N/A
Active, not recruiting	`NCT05283148` - Sickle Cell Disease (SCD) Bone Pain Study	N/A
Completed	`NCT03839732` - Observer Variability in Scoring Abdominal Aortic Calcifications and Vertebral Morphometry
Recruiting	`NCT04609150` - Vertebral Fat Quantitative MRI as a Marker of Bone Fragility in Multiple Myeloma (MYELOMEFRAGIQUANTI)
Completed	`NCT03263585` - Treatment With a Spinal Orthosis Compared to Equipment Group Training and a Control Group	N/A
Completed	`NCT02536898` - Norwegian Capture the Fracture Initiative	N/A
Completed	`NCT01963039` - A Trial of Vertebroplasty for Painful Chronic Osteoporotic Vertebral Fractures (Vertos V)	N/A
Completed	`NCT01120197` - Study of Effect of Exercise With Osteoporosis and Vertebral Fracture	N/A
Recruiting	`NCT04821739` - RISE - Study of the AGN1 LOEP SV Kit in Patients With Vertebral Compression Fractures	N/A
Completed	`NCT05071625` - CT Guided Percutaneous Vertebroplasty for Vertebral Non-union Following Posterior Fixation
Recruiting	`NCT04533217` - Examination of Vertebroplasty in Addition to Regular Treatment of Patients With Multiple Myeloma.	N/A
Completed	`NCT05227976` - Patient Education With or Without Physical Training or Mindfulness and Medical Yoga in Established Spinal Osteoporosis	N/A
Completed	`NCT04980131` - Application of 3-Dimensional Printing Guide Template and Pointed Lotus-style Regulator	N/A
Completed	`NCT01839682` - Evaluation of Outcomes of DFine StabiliT Kyphoplasty in Vertebral Compression Fractures Due to Osteoporosis	N/A
Completed	`NCT03617094` - Early Percutaneous Vertebroplasty Versus Standard Conservative Treatment in Thoracolumbar Vertebral Fractures	N/A
Active, not recruiting	`NCT01374412` - Investigation of Bone Defects and Microcirculation With Computed Tomography and Magnetic Resonance Imaging
Completed	`NCT01817933` - Integrated Rehabilitation Program for Fractures	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Osteoporotic Vertebral Fractures and Exercise

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms