Verifying the Correct Position of Intravenous Catheters Clinical Trial
Official title:
Evaluating the Use of Intravenous Bicarbonate as a Tool to Verify the Intravascular Position of an IV Catheter in Children
Sodium bicarbonate injected into a blood vessel transforms to carbon dioxide and water. The
increase in carbon dioxide production can be detected by measuring the exhaled carbon
dioxide in the lungs.
This study is conducted to access the clinical application of measuring exhaled carbon
dioxide to verify the correct position of intravenous catheters.Once the catheter is in the
correct position the injected bicarbonate will be detected as a distinct elevation of
exhaled carbon dioxide. A similar study was already performed in adults and was found
useful. The investigators now extend the clinical application to children.
Extravasation is the unintentional injection or leakage of fluids into the perivascular or subcutaneous space resulting in potential tissue injury. This prospective controlled study, will assesse the diagnostic utility of using intravenous diluted sodium bicarbonate to confirm placement of intravenous (IV) catheters in ventilated children. Diluted sodium bicarbonate will be created using undiluted standard 8.4% (1 meq/mL) sodium bicarbonate mixed in a 1:3 ratio with sterile water to achieve a final diluted concentration of 2.1% (0.25 mEq/mL). In 20 ASA I-II mechanically ventilated children age 2-8 years, the effects of 1 ml/kg of diluted 2.1% sodium bicarbonate or 0.9% normal saline,injected in a randomized order, will be analyzed. All children will have venous blood samples taken prior to injection and 10 minutes after injection for analysis of venous blood pH and electrolytes. ;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Diagnostic