Clinical Trials Logo

Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT06063811
Other study ID # CHANNELED-Registry
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date September 25, 2023
Est. completion date May 15, 2024

Study information

Verified date September 2023
Source Universitätsklinikum Köln
Contact Jakob Lüker, MD
Phone +49 221 478 82851
Email jakob.lueker@uk-koeln.de
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The CHANNELED-Registry is a multicenter retrospective study to (1) systematically assess the mechanism and origin of ventricular tachycardia in patients with end-stage heart failure carrying an left ventricular assist device (LVAD) and (2) to evaluate procedural parameters and outcome of ventricular tachycardia ablation in this special subset of patients.


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 50
Est. completion date May 15, 2024
Est. primary completion date January 15, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - All patients with end-stage heart failure with an LVAD implanted undergoing VT ablation Exclusion Criteria: - Patients <18 years, pregnant women, patients undergoing VT ablation without an LVAD

Study Design


Intervention

Other:
Ablation
VT ablation

Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Universitätsklinikum Köln

Outcome

Type Measure Description Time frame Safety issue
Primary Mechanism of ventricular tachycardia in LVAD patients (descriptive name of scale) Assessment of the mechanism of VT in LVAD patients (e.g LVAD cannula related vs. related to substrate of underlying heart disease) 12 month
Primary Number of patients with ventricular tachycardia recurrence in device interrogation (physiological parameter) Assessment of VT recurrence after ablation: Device interrogation and readout of ICD Holter 12 month
Primary Mortality (physiological parameter) Assessment of mortality after VT ablation. 12 month
Primary Heart failure Hospitalization (physiological parameter) Assessment of Hospitalization for worsening of Heart Failure after VT ablation. 12 month
Secondary Procedure duration (From groin puncture to sheath removal in minutes) Evaluation of the duration of VT ablation procedures in LVAD patients 12 month
Secondary Fluoroscopy time (minutes) Evaluation of the fluroscopy use (in minutes) 12 month
Secondary Radiofrequency energy used for ablation (in watts; e.g. 40 Watts) Evaluation of the maximum RF-energy used for ablation 12 month
Secondary Number of patients suffering from intraprocedural complication (physiological parameter, e.g. hematoma) Evaluation of intraprocedural complications of VT ablation 12 month
See also
  Status Clinical Trial Phase
Recruiting NCT03453645 - Modification of Rhythmic Risk Assessment by Ventricular Tachycardia Ablation
Completed NCT05791032 - Sub Chronic Evaluation for ATP With an Extravascular Placed ICD Lead (STEP ICD) Study N/A
Completed NCT05970120 - A Study of Intracardiac Ultrasound With the NUVISION NAV Ultrasound Catheter N/A
Completed NCT04011631 - Evaluation of the iD-SystemTM, One-Handed Disposable Internal Defibrillation System. N/A
Recruiting NCT03536052 - Ablation at Virtual-hEart pRedicted Targets for VT N/A
Enrolling by invitation NCT02962076 - Study of Cardiac PET/CT Imaging to Guide Ablation Treatment of Ventricular Tachycardia Early Phase 1
Not yet recruiting NCT02784912 - Biomarkers in Risk Stratification of Sustainted Ventricular Tachycardia or Electrical Storm After Ablation N/A
Completed NCT01791543 - Intramural Needle Ablation for Ablation of Recurrent Ventricular Tachycardia N/A
Terminated NCT02891863 - Low Energy Therapy to Convert Ventricular Tachycardias Phase 0
Terminated NCT01546207 - Stepwise Approach To sUbstrate Modification for Ventricular Tachycardia N/A
Completed NCT01294267 - Percutaneous Hemodynamic Support With Impella 2.5 During Scar-related Ventricular Tachycardia Ablation N/A
Terminated NCT00383799 - Iv Amiodarone Versus Iv Procainamide to Treat Haemodynamically Well Tolerated Ventricular Tachycardia Phase 4
Completed NCT04884100 - enHEART - Exploring Full Content of Optical Signals to Enhance Cardiac Arrhythmia Screening N/A
Completed NCT04642963 - Stereotactic Management of Arrhythmia - Radiosurgery in Treatment of Ventricular Tachycardia N/A
Recruiting NCT05377216 - Characterization of Cardiac Electrophysiological Effects of Autonomic Neuromodulation Early Phase 1
Not yet recruiting NCT04990089 - VIVO European Observational Registry
Completed NCT04065893 - Impact of Catheter Ablation of Ventricular Arrhythmias on Suboptimal Biventricular Pacing in Cardiac Resynchronization Therapy
Recruiting NCT03631303 - Post-Extrasystolic Potentiation as a Predictor of Ventricular Arrhythmias
Recruiting NCT03611465 - Creation of a Pace-mapping Atlas on Healthy and Pathological Hearts N/A
Suspended NCT05478213 - Ventricular Tachycardia Mechanisms N/A