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Ventricular Dysfunction, Right clinical trials

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NCT ID: NCT03972865 Completed - Clinical trials for Ventricular Arrythmia

Cardiovascular Consequences in Intense and Extended Physical Exercise

PHILIPPIDES
Start date: August 14, 2019
Phase: N/A
Study type: Interventional

This research study because you participate in long distance triathlon of Embrun. In recent years, there has been a craze for races at increasingly longer distances (ultra-endurance) with risks to the cardiovascular system poorly identified. In the short term, cardiac functional ultrasonographic changes and disturbances of biomarkers such as troponin are reported in participants in long-term endurance trials, assuming myocardial remodeling and transient tissue damage leading to suffering or "heart fatigue". These constraints could, to the extreme, favor the development of arrhythmia at the atrial and ventricular stages. Cardiac alterations are nevertheless poorly characterized and the consequences, in particular the risk of ventricular rhythm disturbance, have not been studied.The aim of this study is to investigate the relationship between right ventricular functional abnormalities and the occurrence of ventricular rhythm disturbance, following intense and prolonged exercise, in healthy triathletes subjects.

NCT ID: NCT03971331 Not yet recruiting - Clinical trials for Respiratory Distress Syndrome, Adult

The Value of Combined Critical Care Ultrasound and PAC Monitor Oriented Therapy Protocol to Patients of ARDS With ACP

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

We hypothesize that combined critical care ultrasound and PAC monitoring-oriented therapy protocol (CUP protocol), would improve prognosis of patients of ARDS with right ventricular dysfunction. Therefore, the overall goal of the study is: 1) To build the combined critical care ultrasound and PAC monitoring-oriented therapy protocol (CUP Protocol)in detail for patients of ARDS with RV dysfunction. Advantage of CUP protocol is that it directly aims at key parameters that we need for the prevention and treatment of such patients; we could improve the mechanical ventilation protocol, unequal pulmonary lesions, hemodynamics management and reduce pulmonary artery pressure according to these parameters, so that to improve the prognosis of the patients.2) To verify the value of CUP Protocol in ARDS with ACP.

NCT ID: NCT03806582 Completed - Blood Pressure Clinical Trials

Effect of a Higher Blood-pressure on Right Ventricular Function

Start date: March 1, 2019
Phase: Phase 4
Study type: Interventional

Right ventricular (RV) dysfunction in cardiac surgery is an independent risk factor for morbidity and mortality. Raising the systemic blood pressure with norepinephrine seems to have a positive influence on the right ventricular function in several animal studies. The current study is designed to evaluate the effect of a higher blood pressure on the RV function in post cardiac surgery patients.

NCT ID: NCT03701997 Enrolling by invitation - Clinical trials for Ventricular Dysfunction

Registry to Monitor Berlin Heart EXCOR® Pediatric VAD as a Bridge to Cardiac Transplantation.

Start date: October 15, 2018
Phase:
Study type: Observational [Patient Registry]

The purpose of this post market surveillance is to continue monitoring the safety and effectiveness of the Berlin Heart EXCOR® Pediatric. This surveillance includes an "all-comers" prospective cohort of pediatric (<22 years of age) patients implanted according to the IFU with the EXCOR® Pediatric.

NCT ID: NCT03659851 Recruiting - Clinical trials for Left Ventricular Dysfunction

Levosimendan In Patients Undergoing LVAD Implantation

Start date: June 1, 2009
Phase:
Study type: Observational [Patient Registry]

According to the results from the literature, it has been shown that levosimendan usage 24-48 hours before LVAD implementation can improve short and long-term outcome in these patients regarding to the patients without preoperative pretreatment. The aim is to compare short and long-term outcome in patients who underwent to LVAD implementation and pretreated with levosimendan regarding the patient without pretreatment or with other medications.

NCT ID: NCT03581877 Completed - Clinical trials for Pulmonary Hypertension

Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PE

Start date: January 28, 2019
Phase: Phase 4
Study type: Interventional

To determine whether peripheral low dose systemic thrombolysis (PLST) is non-inferior to catheter directed acoustic pulse thrombolysis (ACDT) in improving RV function and reducing pulmonary artery pressures in submassive pulmonary embolism (PE)

NCT ID: NCT03549052 Not yet recruiting - Clinical trials for Right Ventricular Dysfunction

Right Ventricular Echo Assessment in Mitral Valve Replacement

Start date: June 1, 2018
Phase:
Study type: Observational

Rheumatic heart disease remains a major health problem in developing countries. It is the most important sequel of rheumatic fever and occurs in about 30% of patients with rheumatic fever.Rheumatic heart disease presents with different degrees of pancarditis and associated valve failure. Involvement of the mitral leaflets can cause mitral regurgitation (MR) or stenosis and eventually can lead to heart failure. Mitral repair or replacement is therefore recommended before left ventricular (LV) dysfunction develops. Study Objectives/Specific Aims Overall Goal: To determine the benefit the patient with pulmonary hypertension will get from mitral valve replacement as regard function improvement and remodeling of the right ventricle. - Objective1: Identify risk factors that are predictive of outcomes.(Type and severity of Mitral valve pathology , severity of pulmonary hypertension, tricuspid regurge, preoperative RV dysfunction) - Objective2: Determine the value of management strategies (Mitral valve replacement in pulmonary hypertension i.e. : decrease RV pressure overload and enhance RV remodeling) - Objective3: Assessment of the outcomes clinically & Echocardiographically : postoperative results during hospital stay and follow up (short term up to 3 months).

NCT ID: NCT03438825 Completed - Clinical trials for Mitral Valve Disease

PRediction of Early PostoperAtive Right vEntricular Failure in Mitral Valve Replacement/Repair Patients

PREPARE-MVR
Start date: October 2016
Phase:
Study type: Observational

The PREPARE-MVR (PRediction of Early PostoperAtive Right vEntricular failure in Mitral Valve Replacement/Repair patients) Study aims to evaluate those preoperative factors which can predict the early postoperative right ventricular failure or determine the functional shift seen in right ventricular function after mitral valve replacement/repair. The PREPARE-MVR study focuses mainly on echocardiographic (both conventional and advanced) parameters and includes right heart catheterization intraoperatively and in the early postoperative period as gold standard method.

NCT ID: NCT03403868 Recruiting - Clinical trials for Right Ventricular Dysfunction

Right Ventricular Haemodynamic Evaluation and Response to Treatment

Rightheart I
Start date: January 1, 2016
Phase: N/A
Study type: Interventional

Mono-center Study to evaluate different multimodal functional parameter of the right ventricle in PAH-patients

NCT ID: NCT03309852 Recruiting - Cardiac Arrest Clinical Trials

Emergency Department Assessment of Right Ventricular Function and Size in the Post Cardiac Arrest Patient

Start date: October 6, 2017
Phase:
Study type: Observational

The right side of the heart of often overlooked in patients who are acutely unwell, as the main area of focus when performing echocardiography tends to be the left ventricle. The right ventricle can yield important diagnostic clues that can aid the clinician, particularly in cases where one may suspect elevated right sided pressures, such as those due to a pulmonary embolus. Although it is taught that a dilated right ventricle is associated in patients with pulmonary embolus, but in patients with spontaneous circulation. What is unknown is patients who sustain a cardiac arrest, does the same hold true. There is a paucity of literature surrounding the appearance of the right ventricle in the cardiac arrest patient acutely. This study aims to assess right ventricular size and function in the immediate post cardiac arrest phase.