Novel Oxygenation Indices in Robot-Assisted Laparoscopic Surgeries

Status Active, not recruiting

Clinical Trial Summary

In this study, changes in new oxygenation indices investigated by Asar et al. will be compared with conventional oxygenation and saturation indices in patients undergoing robot-assisted laparoscopic surgery due to pneumoperitoneum and Trendelenburg position.

Clinical Trial Description

During the intraoperative period, optimal oxygenation should be achieved while avoiding the harmful effects of hypoxia and hyperoxia in patients. The PaO2/FiO2 and SpO2/FiO2 ratios have been traditionally used to assess this condition. Subsequently, oxygenation indices incorporating mean airway pressure have been developed, such as the oxygenation index (OI = (FiO2 × Pmean) / PaO2) and oxygenation saturation index (OSI = (FiO2 × Pmean) / SpO2). More recently, Asar et al. have defined 8 novel oxygenation indices using mean power (MP) and driving pressure (DP) instead of Pmean (OSI-MPtot, OI-MPtot, OSI-ΔPinsp, OI-ΔPinsp, OSI-MPdyn, OI-MPdyn, PaO2/(FiO2xPEEP), and SpO2/FiO2xPEEP). They compared the predictive power of these new indices for intensive care unit (ICU) mortality in COVID-ARDS (C-ARDS) patients with conventional oxygenation indices (PaO2/FiO2, SpO2/FiO2, OI, OSI). OI-ΔPinsp, OSI-ΔPinsp, and OSI-MPdyn indices were found to have the highest predictive power for ICU mortality. However, there is currently no study investigating the changes of these new indices during the intraoperative period. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06430606
Study type	Observational [Patient Registry]
Source	Basaksehir Çam & Sakura City Hospital
Contact
Status	Active, not recruiting
Phase
Start date	May 1, 2024
Completion date	July 15, 2024

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT06296173` - Open Lung Protective Extubation Following General Anesthesia	N/A
Not yet recruiting	`NCT03245684` - Assisted or Controlled Ventilation in Ards (Ascovent)	N/A
Completed	`NCT03401463` - Assesment of the Endotracheal Tube Cuff Pressure Values in ICU Pateints Before and After Training Seminar	N/A
Completed	`NCT02386683` - Intraoperative Lung-Protective Ventilation in Neurosurgery	N/A
Completed	`NCT03651817` - Lung Protection Strategy in Open Heart Surgery: Which Tidal Volume is Better 8ml/kg or 6ml/kg	N/A
Recruiting	`NCT03709199` - Long Term Follow up of Children Enrolled in the REDvent Study
Recruiting	`NCT03367221` - Physiological Response in Lung Transplant Recipients Undergoing Neurally Adjusted Ventilatory Assist	N/A
Completed	`NCT03056885` - Inflammatory Local Response During OLV: Protective vs Conventional Ventilation Strategy	N/A
Recruiting	`NCT03746236` - Transpulmonary Pressure Under Stressing Conditions
Not yet recruiting	`NCT06334523` - Ventilation of the Extremely Premature Infants Optimized by Dead Space Washout	N/A
Recruiting	`NCT03719365` - Driving Pressure Variation: NAVA vs PSV	N/A
Completed	`NCT03659552` - Percutaneous Temporary Placement of a Transvenous Phrenic Nerve Stimulator for Diaphragm Pacing Using Jugular Access	N/A
Completed	`NCT02732041` - Asynchrony During Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome
Terminated	`NCT03525691` - Enhanced Lung Protective Ventilation With ECCO2R During ARDS	N/A
Not yet recruiting	`NCT05859906` - The Effect of Two Different Intra-abdominal Pressure Applications on "Mechanical Power" in Laparoscopic Cholecystectomy
Recruiting	`NCT05977153` - CT for Personalized Mechanical Ventilation	N/A
Recruiting	`NCT04484727` - "Lung Barometric Measurements in Normal And in Respiratory Distressed Lungs"
Recruiting	`NCT05991258` - Effect of End-inspiratory Airway Pressure Measurements on the Risk of VILI in Ventilated Patients
Terminated	`NCT03951064` - Providing Optimal PEEP During Mechanical Ventilation for Obese Patients Using Esophageal Balloon	N/A
Recruiting	`NCT03945409` - New Automated System for Continuous Real-time Monitoring of Transpulmonary Pressure