Ventilator Associated Pneumonia Clinical Trial
Official title:
Comparison of Two Different Measurement of Endotracheal Tube Cuff Pressure for Ventilatory Associated Pnemonia in Severe Brain Injured Patients
Verified date | May 2020 |
Source | Bagcilar Training and Research Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational [Patient Registry] |
The effect of endotracheal cuff pressure measurement technique for preventing ventilatory associated pneumonia.
Status | Completed |
Enrollment | 30 |
Est. completion date | January 1, 2020 |
Est. primary completion date | April 15, 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 70 Years |
Eligibility |
Inclusion Criteria: Patients with ASA classification of 1 - 2- 3 patients Patients required mechanical ventilation support for more than 48 hours Patients diagnosed with Traumatic brain injury Exclusion Criteria: Official patient relatives who rejected to give informed consent for the study Patients diagnosed with aspiration pneumonia during ICU follow up Patients diagnosed with Acute Respiratory Distress Syndrome Patients diagnosed with cavitary lung lesion Primary lung cancer Metastatic lung cancer Congenitally immune deficiency Leukopenia Neutropenia Tracheostomized patients Post cardiopulmonary arrest patients Pregnancy |
Country | Name | City | State |
---|---|---|---|
Turkey | Bagcilar Training and Research Hospital | Istanbul |
Lead Sponsor | Collaborator |
---|---|
Bagcilar Training and Research Hospital |
Turkey,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Duration | Follow up duration in ICU | 30 days | |
Primary | Ventilation | Mechanically ventilated period | 30 days | |
Primary | Score | Clinical Pulmonary Infection Score Change from baseline at 48.hour, 72.hour and 96.hour | 48.hour - 72.hour - 96.hour | |
Primary | CRP | C Reactive Protein measurement change from Baseline at 48.hour, 72.hour and 96.hour | 48.hour - 72.hour - 96.hour | |
Primary | Oxygenation | Fractional Inspiratory Oxygen levels change from baseline at 48.hour, 72.hour and 96.hour | 48.hour - 72.hour - 96.hour | |
Primary | PEEP | Positive End Expiratory Pressure levels change from baseline at 48.hour, 72.hour and 96.hour during ventilatory support | 48.hour - 72.hour - 96.hour | |
Secondary | Tracheal aspirate | Tracheal aspirate sample for culture | 0.hour - 48.hour - 72.hour - 96.hour | |
Secondary | Bacterial distribution | Bacterial distribution of tracheal aspirate culture | 0.hour - 48.hour - 72.hour - 96.hour | |
Secondary | Mortality | Total mortality ratio during study period | 30 days |
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