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Clinical Trial Summary

In this study, the utility of changes in the ratio of Ret-He and NLR as an early inflammation marker for VAP will be evaluated.


Clinical Trial Description

Ventilator-associated pneumonia (VAP) is one of the most common nosocomial infections in the intensive care unit, affecting one third of patients requiring mechanical ventilation for a noninfectious reason. In the case of inflammation, iron retention increases in the reticuloendothelial system cells; hemoglobin (Hb) synthesis is reduced. It has been reported that the ratio of reticulocyte / hemoglobin (Ret-He) decreases in the early period in community-acquired pneumonia patients and may be a guide as a marker of inflammation. In addition, the neutrophil / lymphocyte ratio (NLR) is a parameter studied in the hemogram panel. It provides a clue to both the presence of infection and the focus of the infection. In this study, the utility of changes in the ratio of Ret-He and NLR as an early inflammation marker for VAP will be evaluated. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04620941
Study type Observational [Patient Registry]
Source Mugla Sitki Koçman University
Contact
Status Suspended
Phase
Start date February 21, 2020
Completion date September 21, 2023

See also
  Status Clinical Trial Phase
Recruiting NCT04926493 - Structural and Microbiological Characterization of Endotracheal Tube Biofilm in Patients at Increased Risk for the Development of Ventilator-associated Pneumonia in the Intensive Care Unit
Terminated NCT01853982 - Study of Intravenous Ceftolozane/Tazobactam Compared to Piperacillin/Tazobactam in Ventilator-Associated Pneumonia Phase 3
Completed NCT01808092 - A Study Comparing Ceftazidime-Avibactam Versus Meropenem in Hospitalized Adults With Nosocomial Pneumonia Phase 3