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Evaluation of Thromboprophylaxis Appropriateness in Hospitalized Medical Patients

Pulmonary Embolism Clinical Trial

Official title:
Evaluation of the Appropriateness of Venous Thromboprophylaxis in Hospitalized Medical Patients Employing the Padua Prediction Score: an Observational Study

Clinical Trial Summary

Considering observational studies that suggested a relationship between acutely ill medical patients and venous thromboembolism (VTE), interventional studies with anticoagulant medications indicated a marked decline in VTE during and after hospitalization. Despite the therapeutic value of lowering this result, there is a low inclination to utilize anticoagulants in patients hospitalized for acute medical diseases. This observational research aims to assess the appropriateness of venous thromboprophylaxis offered to patients admitted to internal medicine wards.

Clinical Trial Description

Epidemiological studies have shown a significant prevalence of thromboembolism in patients admitted to medical wards. Based on this, various clinical studies using anticoagulants such as unfractionated heparin (UFH), low-molecular-weight heparin (LMWH), and fondaparinux to prevent thromboembolism have been conducted in patients hospitalized for acute medical illness. Interventional studies have repeatedly shown that anticoagulant prophylaxis lowers the incidence of deep venous thrombosis (DVT), pulmonary embolism (PE), and DVT-related mortality. These findings led to recommendations to employ anticoagulant prophylaxis in patients hospitalized for acute medical disease; yet, anticoagulant prophylaxis is often underutilized in-hospital medical wards. This study's primary objective is to assess the adequacy of venous thromboprophylaxis delivered to medical inpatients who need pharmacologic intervention in accordance with the American College of Chest Physicians (ACCP) guideline using the Padua prediction score. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05449808
Study type Observational
Source Al-Esraa University College
Contact Laith G. Shareef, F.I.B.M.S.
Phone 009647702884263
Email laith-shareef@esraa.edu.iq
Status Recruiting
Phase
Start date November 13, 2022
Completion date February 1, 2023
View Details
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