Venous Thrombosis Clinical Trial
Official title:
Does the Intraoperative Administration of Tranexamic Acid (TXA) Increase the Incidence of Deep Venous Thrombosis in Total Knee Arthroplasty?
This is an observational trial to estimate the incidence of deep vein thrombosis (DVT) in total knee replacement patients who received an intraoperative dose of tranexamic acid.
This study is anticipated to consist of 30 participants over 18 years of age scheduled for total knee arthroplasty at Sandoval Regional Medical Center with administered intraoperative tranexamic acid, who do not meet the exclusion criteria. The patients will be examined on postoperative day 1. Lower-extremity ultrasound will be used to screen for deep vein thrombosis (DVT). Incidence data for DVT will then be compared with the historical incidence rate at our institution for total knee arthroplasty without the use of tranexamic acid, which is approximately 12%. Patients found on screening to have deep vein thrombosis will be referred for appropriate care. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02567903 -
Tourniquet Study: A Clinical Trial Into the Effect of Tourniquet Use on the Coagulation System
|
N/A | |
Completed |
NCT02247414 -
Warfarin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy and Azygoportal Disconnection
|
Phase 4 | |
Recruiting |
NCT02650453 -
Ongoing Registry of Deep Venous Reconstructions
|
N/A | |
Completed |
NCT02065388 -
Pharmacogenetic Dosing of Warfarin
|
Phase 3 | |
Completed |
NCT00839657 -
Clarification of Optimal Anticoagulation Through Genetics
|
Phase 3 | |
Terminated |
NCT00872079 -
Personalized Warfarin Dosing by Genomics and Computational Intelligence
|
N/A | |
Terminated |
NCT00521885 -
Comparison of Arixtra vs. Lovenox to Prevent Blood Clots in Medically Ill Patients
|
N/A | |
Completed |
NCT02892565 -
Hypercoagulable Phenotype by Thrombinography (in Presence of C Protein Dynamic Inhibitory System)
|
N/A | |
Completed |
NCT00346424 -
Safety and Efficacy Study of Alfimeprase in Subjects With Occluded Central Catheters
|
Phase 3 | |
Active, not recruiting |
NCT04349189 -
Venous Thrombosis Biomarkers in Sickle Cell Disease and Sickle Cell Trait
|
||
Recruiting |
NCT02238444 -
Warfarin Prevents Portal Vein Thrombosis in Liver Cirrhotic Patients With Hypersplenism After Laparoscopic Splenectomy
|
Phase 4 | |
Recruiting |
NCT02597218 -
Incidence of Venous Thromboembolic Disease and Portal Vein Thrombosis After Hepatectomy. A Cohort Study.
|
||
Completed |
NCT00986154 -
Comparative Investigation of Low Molecular Weight (LMW) Heparin/Edoxaban Tosylate (DU176b) Versus (LMW) Heparin/Warfarin in the Treatment of Symptomatic Deep-Vein Blood Clots and/or Lung Blood Clots. (The Edoxaban Hokusai-VTE Study).
|
Phase 3 | |
Completed |
NCT00246025 -
A Study of BIBR 1048 in Prevention of Venous Thromboembolism in Patients With TKR Surgery.
|
Phase 2 | |
Completed |
NCT00097357 -
BMS-562247 in Subjects Undergoing Elective Total Knee Replacement Surgery
|
Phase 2/Phase 3 | |
Completed |
NCT04645550 -
Apixaban, Warfarin and Aspirin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy(ESAWAAPT)
|
Phase 4 | |
Recruiting |
NCT02264743 -
Oral Verses Patch Trial In Menopausal Women - Individualisation of Oestrogen Therapy
|
Phase 4 | |
Completed |
NCT01482273 -
Ultrasound-enhanced Thrombolysis Versus Standard Catheter Directed Thrombolysis for Ilio-femoral Deep Vein Thrombosis
|
N/A | |
Recruiting |
NCT01252420 -
Two Weeks of Low Molecular Weight Heparin for Distal Vein Thrombosis
|
Phase 4 | |
Completed |
NCT01145859 -
Rivaroxaban Pharmacokinetics/Pharmacodynamics (PK/PD) Study in Pediatric Subjects
|
Phase 1 |