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Clinical Trial Summary

Arteriovenous malformation (AVM) is a congenital vascular anomaly that progresses throughout life and causes complications including tissue destruction due to rapid overgrowth, bleeding, functional deficits, severe deformity and cardiac failure. Unfortunately, traditional managements have transient benefits with more than 90 recurrence rate within a year. Therefore, there is a significant unmet medical need. The purpose of this study is to assess the safety and efficacy of Trametinib in children and adults with Extracranial Arteriovenous Malformation (AVM).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04258046
Study type Interventional
Source Stanford University
Contact
Status Recruiting
Phase Phase 2
Start date December 1, 2020
Completion date December 31, 2024

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