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Vasopressor clinical trials

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NCT ID: NCT03805230 Completed - Clinical trials for Surgical Procedures, Operative

Postoperative Vasopressor Usage: SQUEEZE

SQUEEZE
Start date: October 5, 2020
Phase:
Study type: Observational

A prospective multi-centre international observational study of postoperative vasopressor use, designed to answer the question: 'What is the proportion of patients that receive vasopressor infusions? In the management of these patients; - Are there variations in the practice between clinicians, hospitals or countries? If yes, are they associated with clinical outcome? - What are the health economic impacts associated with receiving vasopressors?

NCT ID: NCT03706755 Completed - Anesthesia Clinical Trials

Comparison of Two Doses of Norepinephrine in Preventing Hypotension After Spinal Anesthesia

Start date: May 3, 2018
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine the more effective intravenous bolus of norepinephrine for maintaining blood pressure during a spinal anesthesia for a cesarean delivery with the fewer side effects. Low blood pressure has been shown to decrease uterine perfusion and foetal outcomes during cesarean delivery under spinal anesthesia. For elective or semi-urgent cesarean delivery, all participants will receive spinal anesthesia with a local anesthetic and either sufentanil or fentanyl. This study plans to enroll 124 pregnant women. Patients will be randomly assigned according to a computer generated system to be in one of two groups.

NCT ID: NCT01669213 Active, not recruiting - Hypotension Clinical Trials

Effects of Different Kinds, Different Doses of 5-HT3 Receptor Antagonists on Prevention of Hypotension

Start date: August 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to estimate effects of different kinds, different dose of 5-HT3 receptor antagonists on prevention of hypotension after spinal anesthesia

NCT ID: NCT01483209 Terminated - Ischemia Clinical Trials

Treatment of Vasopressor-induced Ischemia With Botulinum Toxin A

Start date: March 2012
Phase: N/A
Study type: Interventional

The goal of this project is to determine if performing a "chemical sympathectomy" by injecting botulinum toxin A in critically ill patients on vasopressors can treat digital ischemia. This is a prospective, non-randomized pilot study designed to demonstrate proof of concept. We propose to study patients in the intensive care units of Duke Hospital who, secondary to exposure to vasoactive medications used to maintain acceptable blood pressures, have developed signs and symptoms of digital ischemia. A paired T-test will be used to compare pre- and post-injection Laser Doppler measurements for the experimental hand. We will again use a paired t-test to compare the experimental hand against the contralateral control hand. There were no major adverse events reported by the product information sheet or in other related studies of Botox for digital ischemia.