Use of Discarded Surgery Human Tissue Specimens for Basic Science Research

Vascular Calcification Clinical Trial

— HumTisRes  

Official title:

Use of Discarded Surgery Human Tissue Specimens for Basic Science Research

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04753593
• Other study ID #: PI2021_843_0002
• Status: Recruiting
• Start date: March 16, 2021
• Est. completion date: February 2026

Study information

• Verified date: February 2023
• Source: Centre Hospitalier Universitaire, Amiens
• Contact: Romuald Mentaverri, Pr
• Phone: 03 22 887104
• Email: romuald.mentaverri[@]u-picardie.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Although it is now established that calcification process result from the joint and coordinated action of different cell types, many areas of shadow remain regarding the spatio-temporal implementation of these events. Highlighting these processes requires additional research to consider new approaches to clinical management of patients with such conditions. It is in this context that the investigators need to use residual human tissue fragments resulting from surgery which are not intended to be used for clinical-biological management of patients. The use of these pseudonymised human tissues will allow the investigators to conduct in vitro cell culture experiences.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 200
• Est. completion date: February 2026
• Est. primary completion date: February 2026
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients undergoing surgery in the Cardiac Surgery and Orthopedic Surgery departments of the CHU Amiens-Picardie

• patients who will be beforehand informed

• patients who will not be opposed to this study.

Exclusion Criteria:

• HIV and hepatitis positive patients

Related Conditions & MeSH terms

• Calcinosis
• Osteoblast
• Vascular Calcification

Locations

Country	Name	City	State
France	CHU Amiens	Amiens

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire, Amiens

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Success in establishment of Cell Culture Systems from discarded surgery specimens	Success in establishment of Cell Culture Systems from discarded surgery specimens	5 years