Valve Heart Disease Clinical Trial
Official title:
Long-term Outcomes of Bioprothetic Valve Versus Mechanical Valve
In this study, the investigators aim to use data identified through the hospital's integrated medical database and National Health Insurance database to explore the long-term performance and benefits of biological and mechanical valves. This research aims to provide more recommendations and references for valve replacement in different patient populations.
Long-term follow-up of valve surgery is essential in all cardiac surgeries and is the most commonly discussed indicator. The choice of valves has evolved over the past 30 years, offering two options: biological valves and mechanical valves. Biological valves have seen advancements in the last 15 years, including new processes and improved valve preservation methods. The question of whether these new process valves offer better long-term effectiveness has become a hot research topic in recent years. Mechanical valves have a longer lifespan, but the need for long-term anticoagulant use to prevent mechanical valve thrombosis has raised concerns about anticoagulant side effects, abnormal clotting function, and bleeding. Biological valves, on the other hand, do not require long-term anticoagulation and only necessitate 2-3 months of anticoagulant treatment. However, the risk of biological valve degeneration results in an average lifespan of 10 to 20 years, which cannot match the durability of mechanical valves. This is the drawback of using biological valves. Therefore, the investigators hope to utilize the hospital's integrated medical database and the long-term National Health Insurance database for tracking. The investigators aim to observe valve performance in different patient groups, such as young people, the elderly, patients on dialysis, those with rheumatic autoimmune diseases, and those taking specific medications, among others. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT06066970 -
Cardiac Biomarkers for the Quantification of Myocardial Damage After Cardiac Surgery
|
||
Recruiting |
NCT05079672 -
Efficacy and Safety of Dexmedetomidine in the Analgesic Prophylaxis , in Patients Undergoing Cardiovascular Surgery
|
Phase 4 | |
Completed |
NCT03347851 -
Post-surgical Aortic Hemodynamics After Aortic Valve Replacement
|
||
Active, not recruiting |
NCT03539458 -
Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification
|
N/A | |
Completed |
NCT04328090 -
Evaluation of the Potential Impact of Computerized Antimicrobial Stewardship
|
N/A | |
Recruiting |
NCT04359030 -
Freestyle-Perimount Calcification Comparison
|
||
Completed |
NCT04958668 -
Prospective Evaluation of Volatile Sedation After Heart Valve Surgery
|
N/A | |
Completed |
NCT04598360 -
Release of Epoxyeicosatrienoic Acids From Erythrocytes During the Use of Extracorporeal Procedures (Heart-lung Machine)
|
N/A | |
Not yet recruiting |
NCT04118621 -
Role of Chest Ultrasound in Detection of Post-operative Pulmonary Complications After Cardiothoracic Surgery
|
||
Recruiting |
NCT06387446 -
Allogeneic Valve Transplantation
|
N/A | |
Recruiting |
NCT04843072 -
Balloon vs. Self Expanding Transcatheter Valve for Degenerated Bioprosthesis
|
N/A | |
Completed |
NCT05804500 -
RecoveryPlus Telerehab Platform Pilot Study
|
N/A | |
Recruiting |
NCT03885180 -
Randomized Evaluation of D-dimer Guiding dUration of Oral antiCoagulation thErapy
|
N/A | |
Completed |
NCT06154018 -
Heparin Reversal With Two Different Protamine Ratios After Cardiopulmonary By-pass.
|
N/A | |
Suspended |
NCT01571791 -
Perioperative Ketorolac-lidocaine in the Patients With Valvular Heart Diseases During Cesarean Delivery
|
Phase 2 | |
Completed |
NCT06261788 -
Efficacy and Safety of the Sync-AV II Temporary Cardiac Pacing Catheter
|
N/A | |
Completed |
NCT06079008 -
The Association of Cardiac Valve Calcification and 1-year Mortality After Lower-extremity Amputation in Diabetic Patients
|
||
Completed |
NCT04372654 -
Pilot Study Evaluating the Safety of Electroducer Sleeve Medical Device for Temporary Cardiac Stimulation During Percutaneous Cardiovascular Interventions, in All Kind of Patients
|
N/A | |
Active, not recruiting |
NCT03661398 -
Caisson Transcatheter Mitral Valve Replacement (TMVR)
|
N/A | |
Recruiting |
NCT03595423 -
SPAnish Aortic VALVE Multicentric Study
|