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Ocular Pathogen and Transcriptome Investigation Using Comprehensive Sequencing — OPTICS  

Uveitis Clinical Trial

Official title:
Ocular Pathogen and Transcriptome Investigation Using Comprehensive Sequencing

Clinical Trial Summary

This is a multi-center randomized controlled evaluator-masked trial designed to compare metagenomic deep sequencing (MDS) versus standard of care testing for improvement of outcomes for intraocular infections. Patients with presumed intraocular infections who meet the eligibility criteria will be randomized to receive MDS testing results or not to receive MDS testing results. All patients will receive standard-of-care testing to guide management. Enrolled patients will be followed at week 2, week 3-6 (randomization visit), and at 4 weeks after the randomization visit. The proportions of patients who received the appropriate therapy and the proportions of patients with improved outcome will be compared between arms. Patient quality of life, MDS performance, and the provider certainly of belief will be collected.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05286203
Study type Interventional
Source University of California, San Francisco
Contact Jessica Shantha, MD
Phone (415) 476-1442
Email Jessica.shantha@ucsf.edu
Status Recruiting
Phase N/A
Start date June 6, 2022
Completion date December 2026
View Details
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