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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT01905579
Other study ID # TEC 123
Secondary ID TEC 2012-003
Status Completed
Phase N/A
First received July 18, 2013
Last updated August 29, 2014
Start date March 2013
Est. completion date August 2013

Study information

Verified date August 2014
Source The Eye Center and The Eye Foundation for Research in Ophthalmology
Contact n/a
Is FDA regulated No
Health authority Saudi Arabia: Ministry of Health
Study type Interventional

Clinical Trial Summary

The purpose of this study is to compare flaremetry readings with the protein content of the aqueous humor and the clinical grading of flare.


Description:

A total of 20 patients will be included. 10 patients with uveitis and 10 control patients scheduled for phacoemulsification. Each patient will undego complete ophthalmic examination and clinical biomicroscopic grading of the anterior chamber flare applying the SUN working group grading system. Aqueous specimens will be obtained by anterior chamber paracentesis for protein analysis. Each Patient will undego paracentesis and 0.2 ml of aqueous will be obtained. The aqueous sample will be stored at -70°C until the time of analysis for protein content. Objective assessment of flare will be done.


Recruitment information / eligibility

Status Completed
Enrollment 20
Est. completion date August 2013
Est. primary completion date July 2013
Accepts healthy volunteers No
Gender Both
Age group 10 Years to 80 Years
Eligibility Inclusion Criteria:

- 10 patients with uveitis with cataract

- 10 patients without uveitis with cataract

- Inactive inflammation for at least 3 months

Exclusion Criteria:

- Infectious uveitis

- endophthalmitis

- cases with corneal scar

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic


Related Conditions & MeSH terms


Intervention

Procedure:
Paracentesis of the anterior chamber
Aqueous humor parenthesis for quantitative protein analysis in patients with and without uveitis.

Locations

Country Name City State
Saudi Arabia The Eye Center Riyadh

Sponsors (1)

Lead Sponsor Collaborator
The Eye Center and The Eye Foundation for Research in Ophthalmology

Country where clinical trial is conducted

Saudi Arabia, 

Outcome

Type Measure Description Time frame Safety issue
Primary compare flaremetry readings with the protein content of the aqueous humor Compare flaremetry readings with the protein content of the aqueous and the clinical grading. one month No
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