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Uterine Neoplasms clinical trials

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NCT ID: NCT05344950 Recruiting - Colorectal Cancer Clinical Trials

Connecting Audio and Radio Sensing Systems to Improve Care at Home

AURA
Start date: March 21, 2022
Phase: N/A
Study type: Interventional

This is a proof-of-concept pilot randomized clinical trial to test the usability and feasibility of the innovative Audio + Radio (AURA) system to enhance personalized supportive care for cancer patients and caregivers during post-ostomy care transition.

NCT ID: NCT05242861 Recruiting - Ovarian Neoplasms Clinical Trials

Retrospective Study of Brachytherapy

RetroBT
Start date: February 20, 2022
Phase:
Study type: Observational

Brachytherapy for gynecological cancers will be studied retrospectively.

NCT ID: NCT05220033 Recruiting - Ovarian Cancer Clinical Trials

Journey Ahead: Enhancing Coping and Communication for Women Diagnosed With Gynecological Cancer

Start date: July 14, 2020
Phase: N/A
Study type: Interventional

This study looks at how well the Journey Ahead intervention works in improving coping and communication skills in participants with gynecologic cancers.

NCT ID: NCT05147558 Recruiting - Clinical trials for Uterine Carcinosarcoma

A Study of Pembrolizumab With Lenvatinib in Women With Advanced Uterine Carcinosarcoma

Start date: December 23, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study to find out whether the combination of lenvatinib and pembrolizumab is an effective treatment for advanced uterine carcinosarcoma. The researchers will also do tests to find out whether biomarkers in the blood can predict the cancer's response to the study treatment. A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition

NCT ID: NCT05049538 Recruiting - Clinical trials for Endometrial Serous Adenocarcinoma

Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in High-Risk Endometrial Cancers

Start date: June 18, 2019
Phase:
Study type: Observational

This study is to find out how well liquid biopsies work as a non-invasive alternative to other methods of finding cancer cells (such as a tissue biopsy) in patients with high-risk endometrial cancer. A liquid biopsy is a blood test that may be able to find cancer cells. Collecting and storing samples of blood and tissue from patients with endometrial cancer to study in the laboratory may help doctors learn how the cells in the blood may change during treatment for uterine cancer.

NCT ID: NCT04890912 Recruiting - Endometrial Cancer Clinical Trials

Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus II

SPARTACUSII
Start date: July 15, 2021
Phase: N/A
Study type: Interventional

Adjuvant radiotherapy (RT) plays an important role in reducing the risks of local recurrence after surgery in uterine cancers. Standard adjuvant pelvic radiation treatment targets the pelvic lymph nodes, the post-operative bed, and the upper vagina and is typically treated with intensity modulated radiation therapy (IMRT) which has been shown to improve patient reported gastrointestinal (GI) and genitourinary (GU) toxicities. Although pelvic radiation has been shown to be effective at decreasing locoregional recurrences, patient quality of life and experience can be significantly impacted as pelvic RT comprises of daily radiation for 25 daily treatments, which can be a substantial burden on patients with this disease. Hypofractionated radiotherapy to a dose of 30 Gy in 5 fractions (6 Gy given every other day) for adjuvant radiation treatment in uterine cancer is hypothesized to result in similar rates of acute gastrointestinal toxicities as conventional fractionated radiation.

NCT ID: NCT04849858 Recruiting - Ovarian Cancer Clinical Trials

Pilot Study of Liposomal Bupivacaine Redosing in Patients Undergoing Major Gynecologic Procedures

Start date: May 20, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this research study is to find out which type of transversus abdomens plane (TAP) and block (bupivacaine, liposomal bupivacaine or liposomal bupivacaine with re-dosing at 48-60 hours) improves your pain control and lowers your risk of post-operative common side effects of surgery and narcotic pain medications.

NCT ID: NCT04831437 Recruiting - Cervix Uteri Cancer Clinical Trials

Clinical Response and Toxicity of Hypo-fractionated Chemoradiotherapy in Cervix Cancer

Start date: April 1, 2021
Phase: Phase 2
Study type: Interventional

Uterine cervix cancer can be treated definitively with concurrent chemoradiation (external beam radiotherapy and chemotherapy) followed by high dose rate brachytherapy. Treatment duration can be shortened by increasing the dose per fraction of treatment which can reduce costs and patient exposure. The aim of our study is to determine the non-inferiority of hypofractionated radiotherapy compared with conventional treatment.

NCT ID: NCT04517019 Recruiting - Clinical trials for Head and Neck Cancer

Randomised Trial Evaluating the Benefit of a Fitness Tracker Based Workout During Radiotherapy

OnkoFit II
Start date: August 1, 2020
Phase: N/A
Study type: Interventional

Evaluation of the impact of an activity tracker based fitness programme on the Qualitiy of Life after oncological therapy.

NCT ID: NCT04367415 Recruiting - Intrauterine Polyp Clinical Trials

Darwish Test (Office Hysteroscopic Bubble Suction and Tubal Peristalsis) in Cases of Intrauterine Polyp(s)

Start date: August 20, 2021
Phase:
Study type: Observational

Anatomic Fallopian tubal patency and physiologic patency testing are feasible via hystertoscopy. This study aims to test the impact of different types of intrauterine polyp(s) on Darwish test (office hysteroscopic bubble suction test and tubal peristalsis).