| Eligibility |
Inclusion Criteria:
- CASE TISSUE:
- Patient has a histological diagnosis of primary clear cell RCC, papillary cell
RCC, clear cell papillary RCC, chromophobe RCC, oncocytoma, or urothelial cell
carcinoma
- Age >= 18 years
- CASE BLOODS AND URINE:
- Patient has a histological diagnosis of primary clear cell RCC, papillary cell
RCC, chromophobe RCC, oncocytoma, or urothelial cell carcinoma
- Age >= 18 years
- HEALTHY CONTROL BLOODS AND URINE:
- Patients has undergone negative hematuria workups (defined as negative abdominal
imaging and negative cystoscopy
- Age >= 18 years
Exclusion Criteria:
- CASE TISSUE:
- Patient has von Hippel-Lindau disease (VHL), Hereditary leiomyomatosis and renal
cell cancer (HLRCC), Hereditary papillary renal carcinoma (HPRC), or
Birt-Hogg-Dube syndrome (BHD)
- The current target pathology is a recurrence
- Patient has undergone any prior radiation therapy to target lesion prior to
surgery
- Patient has received chemotherapy class drugs in the 5 years prior to surgery
- Patient has had any transplants prior to surgery
- Patient has confirmation of Lynch Syndrome, is presumed to have Lynch Syndrome,
or has familial cancer syndrome X
- Patient has Nephritis (Glomerulus or Interstitial), Poly Cystic Kidney Disease,
Glomerulonephropathies or Acquired Renal Kidney Disease
- RENAL CONTROL TISSUE:
- Patient has von Hippel-Lindau disease (VHL), Hereditary leiomyomatosis and renal
cell cancer (HLRCC), Hereditary papillary renal carcinoma (HPRC), or
Birt-Hogg-Dube syndrome (BHD).
- Patient has inflammation, atypia, or hyperplasia of the parenchyma
- Patient has a current or past history of renal cancer.
- Patient has undergone any prior radiation therapy to target lesion prior to
surgery
- Patient has received chemotherapy class drugs in the 5 years prior to surgery
- Patient has had any transplants prior to surgery
- Patient has confirmation of Lynch Syndrome, is presumed to have Lynch Syndrome,
or has familial cancer syndrome X
- Patient has Nephritis (Glomerulus or Interstitial), Poly Cystic Kidney Disease,
Glomerulonephropathies or Acquired Renal Kidney Disease
- UROTHELIEAL CONTROL TISSUE:
- Patient has von Hippel-Lindau disease (VHL), Hereditary leiomyomatosis and renal
cell cancer (HLRCC), Hereditary papillary renal carcinoma (HPRC), or
Birt-Hogg-Dubé syndrome (BHD)
- Patient has inflammation, atypia, or hyperplasia of the urothelium
- Patient has a current or past history of urothelial cancer
- Patient has undergone any prior radiation therapy to target lesion prior to
surgery
- Patient has received chemotherapy class drugs in the 5 years prior to surgery
- Patient has had any transplants prior to surgery
- Patient has confirmed or presumed lynch
- CASE BLOODS AND URINE:
- Patient has known primary cancer outside of the kidney within the last 5 years
prior to plasma and urine collection (not including basal cell or squamous cell
skin cancers)
- Patient has had surgery to completely or partially remove current target
pathology
- Patient has undergone any prior radiation therapy to target lesion prior to
plasma and urine collection
- Patient has received chemotherapy class drugs in the 5 years prior to plasma and
urine collection
- Patient has had any transplants prior to plasma and urine collection
- Patient has confirmed or presumed lynch
- Patient has von Hippel-Lindau disease (VHL), Hereditary leiomyomatosis and renal
cell cancer (HLRCC), Hereditary papillary renal carcinoma (HPRC), or
Birt-Hogg-Dubé syndrome (BHD)
- HEALTHY CONTROL BLOODS AND URINE:
- Patient has known primary cancer outside of the urothelium within the last 5
years prior to plasma and urine collection (not including basal cell or squamous
cell skin cancers)
- Current target pathology is a recurrence
- Patient has undergone prior radiation therapy in the 5 years prior to plasma and
urine collection
- Patient has received chemotherapy class drugs in the 5 years prior to plasma and
urine collection
- Patient has had any transplants prior to plasma and urine collection
- Patient has von Hippel-Lindau disease (VHL), Hereditary leiomyomatosis and renal
cell cancer (HLRCC), Hereditary papillary renal carcinoma (HPRC), or
Birt-Hogg-Dube syndrome (BHD)
- Patient has confirmed or presumed lynch
- Gross urinary incontinence
- Patient has undergone cystectomy
|
