Urothelial Carcinoma Clinical Trial
Official title:
Clinical Evaluation of 18F-LN1 PET/CT for Imaging of Nectin-4 in Urothelial Carcinomas
The clinical feasibility of 18F-LN1 PET/CT will be evaluated in 30 patients with urothelial carcinoma, and the results will be compared with those of 18F-FDG.
| Status | Recruiting |
| Enrollment | 30 |
| Est. completion date | October 2024 |
| Est. primary completion date | September 2024 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility | Inclusion Criteria: - Age 18 and above - No gender difference - Patients who have been diagnosed with, or are clinically highly suspected of, urothelial carcinomas and have had no other treatment within 3 months Exclusion Criteria: - Hypertension that is difficult to control with medication, and systolic blood pressure exceeding 160mmHg - Complicated with chronic liver disease, myocardial infarction, stroke - Female patients who are pregnant (or attempting to become pregnant within six months), breastfeeding, or unwilling to use contraception - Abnormal cardiopulmonary function or mental state, unable to tolerate prone lying for 20 minutes |
| Country | Name | City | State |
|---|---|---|---|
| China | Departments of Nuclear Medicine, Sichuan Provincial People's Hospital | Chengdu | Sichuan |
| Lead Sponsor | Collaborator |
|---|---|
| Sichuan Provincial People's Hospital |
China,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Comparison of 18F-LN1 and 18F-FDG Uptake in Patients with urothelial carcinoma | The correlation between the results of PET images and histopathological results | 1 mouth |
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|---|---|---|---|
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