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Urological Manifestations clinical trials

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NCT ID: NCT05989646 Recruiting - Clinical trials for Urinary Incontinence

Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children

Start date: May 5, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to investigate whether the activity in brain areas controlling the bladder is different among children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI) compared to age- and gender-matched healthy children without bladder symptoms. Moreover, the aim is to investigate if sacral transcutaneous electric nerve stimulation (TENS) has a central mechanism of action. Children with OAB and DUI will be recruited from involved pediatric departments, and functional magnetic resonance imaging (fMRI) will be performed before and after 10 weeks of sacral TENS. In healthy children without bladder symptoms, only the baseline fMRI will be performed.

NCT ID: NCT05846555 Recruiting - Anesthesia Clinical Trials

Optic Nerve Sheath Diameter in Urologic Surgery

Start date: April 18, 2023
Phase:
Study type: Observational [Patient Registry]

The investigators aimed to determine intracranial pressure changes during spinal and general anesthesia by using optic nerve sheath diameter and near infrared spectrometer in urologic surgery patients in lithotomy position. Also the investigators plan to evaluate to measure intrathoracic pressure effects to intracranial pressure.

NCT ID: NCT05520151 Not yet recruiting - Clinical trials for Urological Manifestations

"Influence of Preoperative Immunomodulation by Oral Impact® on Postoperative Complications Following Cystectomies and Nephrectomies

IMPACTURO
Start date: September 2022
Phase: Phase 3
Study type: Interventional

any studies have shown the benefit of perioperative Oral Impact immunomodulation in gastrointestinal, ENT, gynaecological and cardiac surgery . Studies in major Urological surgery are rare and are rare and not very contributory. The expected benefit is a reduction in postoperative complications and the average length of stay.

NCT ID: NCT05250908 Recruiting - Clinical trials for Lower Urinary Tract Symptoms

INTIBIA Pivotal Study

Start date: March 7, 2022
Phase: N/A
Study type: Interventional

Prospective, randomized, double-blind, multicenter study to evaluate the safety and efficacy of an implantable tibial nerve stimulator in subjects with urgency urinary incontinence (UUI).

NCT ID: NCT03104907 Completed - Clinical trials for Lower Urinary Tract Symptoms

Prostatic Artery Embolization for Obstructive Uropathy Due to Prostate Cancer

Start date: March 22, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the safety and efficacy of prostatic artery embolization of patients with recurrent symptoms secondary to locally advanced prostatic cancer including pelvic pain, bleeding or need for permanent urinary catheter who are unfit for or refuse surgical treatment.

NCT ID: NCT03099421 Completed - Clinical trials for Lower Urinary Tract Symptoms

Prostatic Artery Embolization for Benign Prostatic Obstruction

Start date: March 22, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the safety and efficacy of prostatic artery embolization (PAE) for patients who refuse or are not eligible for surgery with moderate-severe lower urinary tract symptoms or indwelling catheter secondary to benign prostate obstruction due to benign prostatic hyperplasia.

NCT ID: NCT02573311 Completed - Clinical trials for Urological Manifestations

Actual Use Study of Tamsulosin in Men

Start date: September 23, 2015
Phase: Phase 3
Study type: Interventional

An actual use study to assess how men who respond to advertisements about urinary symptoms use tamsulosin in a simulated Over the Counter (OTC) setting including following "stop use and ask a doctor if" and "ask a doctor before use" statements and if they take the medication according to the label instructions, also assess any reported adverse events during simulated OTC use.

NCT ID: NCT02291432 Completed - Stress Clinical Trials

Autologous Cell Therapy for Stress Urinary Incontinence in Males Following Prostate Surgery

Start date: February 19, 2015
Phase: Phase 1/Phase 2
Study type: Interventional

To study the safety and potential efficacy of Autologous Muscle Derived Cells for Urinary Sphincter Repair (AMDC-USR) for the treatment of male stress urinary incontinence (SUI) for patients that have undergone prior prostate surgery.

NCT ID: NCT01340027 Completed - Urologic Diseases Clinical Trials

A Study to Evaluate the Efficacy, Safety and Tolerability of Mirabegron and Solifenacin Succinate Alone and in Combination for the Treatment of Overactive Bladder

Symphony
Start date: March 29, 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to examine how well two medicines in combination (solifenacin succinate and mirabegron) work in the treatment of bladder problems over a 12-week period.