Urolithiasis Clinical Trial
Official title:
Correlation Between Excretion Metabolites in Urine and Bacterial Microflora in Patients With Urinary Stone Disease
NCT number | NCT01637506 |
Other study ID # | H10-01195 |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | July 2012 |
Est. completion date | December 2022 |
The purpose of this study is to add to the investigators' quest to understanding stone disease, by evaluating the metabolites excretion in urine and its relation to microflora present in the stool.
Status | Recruiting |
Enrollment | 20 |
Est. completion date | December 2022 |
Est. primary completion date | December 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 19 Years to 90 Years |
Eligibility | Inclusion Criteria: Controls - Age > 19. - No history of kidney stone disease Study Patient (Stone Patient) - Age > 19 - Radiological evidence indicating presence of a current renal or ureteric stone Exclusion Criteria: - Pregnancy - Positive Urine Culture - Active cancer - Recurrent urinary infections - Gross hematuria - Inability to provide informed consent - In the Investigator's opinion, the patient would not be good for the study. Controls Only: - Family history of kidney stones - History of kidney stones |
Country | Name | City | State |
---|---|---|---|
Canada | Stone Centre, Vancouver General Hospital, Jim Pattison Pavilion | Vancouver | British Columbia |
Canada | Vancouver General Hospital | Vancouver | British Columbia |
Lead Sponsor | Collaborator |
---|---|
University of British Columbia |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Bacterial flora in the intestine of patients with kidney stones compared to non-stone forming individuals | The objective of this study is to compare the bacterial flora in the intestine of patients with kidney stones compared to non-stone forming individuals. If there are differences between stone forming and non-stone forming individuals in the content of their bacterial flora, these will also be correlated with levels of metabolites found in the urine that are known risk factors of stone disease. Difference in bacterial intestinal flora already exists for patients who are obese compared to non-obese individuals. | one day of urine and stool collection |
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