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Urinary Tract Infections clinical trials

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NCT ID: NCT03108079 Recruiting - Clinical trials for Urinary Incontinence

Bladder Morphology Using 2 Different Catheter Designs

Start date: April 2017
Phase: N/A
Study type: Interventional

Demonstrate and compare the 3D morphology of the bladder wall in full and drained states with 2 different kinds of bladder catheters in place. (Foley Catheter vs. Cystosure Catheter)

NCT ID: NCT03044223 Recruiting - Sepsis Clinical Trials

Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis

MIPSA
Start date: August 2014
Phase:
Study type: Observational

The present study focuses on patients with Pseudomonas aeruginosa (PSA) sepsis. The aim of the present study is to find out whether the M1 (pro-inflammatory) or M2 (anti-inflammatory) phenotype predominates in blood monocytes in critically ill patients with PSA-sepsis, and whether the severity of sepsis and outcome is associated with distinct monocyte phenotype and function.

NCT ID: NCT02979951 Recruiting - Sepsis Clinical Trials

Fosfomycin i.v. for Treatment of Severely Infected Patients

FORTRESS
Start date: December 2016
Phase:
Study type: Observational

The purpose of this European, multicentric, prospective, non-interventional study is to document and evaluate the efficacy and safety of the treatment of severely infected patients with intravenously administered fosfomycin, including patients with osteomyelitis, complicated urinary tract infection, nosocomial lower respiratory tract infection, bacterial meningitis/central nervous system infection, bacteraemia/sepsis, skin and soft tissue infection, endocarditis or other infections, each as far as covered by the respective nationally relevant SmPC.

NCT ID: NCT02973178 Recruiting - Clinical trials for Urinary Tract Infections

Scanadu Urine Device Validation Study Protocol

Start date: August 2016
Phase: N/A
Study type: Interventional

This study will test Scanadu Urine Device for clinical performance and usability.

NCT ID: NCT02829060 Recruiting - Sepsis Clinical Trials

Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2

PNLABXPART2
Start date: January 2016
Phase: N/A
Study type: Interventional

This study will be a multi-institutional randomized clinical trial of a short course of pre-operative antibiotic prophylaxis in addition to perioperative antibiotics prior to undergoing percutaneous nephrolithotomy. The select patient population will be those patients deemed to be at a moderately increased risk of postoperative infectious complications. These higher risk patients are those with indwelling urinary drainage tubes and those with a positive preoperative urine culture.

NCT ID: NCT02789579 Recruiting - Clinical trials for Complication of Surgical Procedure

The Preventive Infection Role of One Week Antibiotics Before Minimally Invasive Upper Tract Lithotomy

Start date: September 2016
Phase: Early Phase 1
Study type: Interventional

Minimally invasive upper tract lithotomy is currently a common operation method on treatment of urinary tract stones, but the postoperative complication urinary tract infection or urinary sepsis has turned into a serious threat to the patient's life, when severe, can result in a higher death rate.Although more the more importance were attached to, an effective prevention measures still have not been found. Among Urinary calculi, the higher rates of infection stone resulted in a higher incidence of postoperative urinary tract infection. The conventional postoperative prophylaxis medicine was the use of antimicrobial drugs half an hour before surgery.Foreign studies had shown that continuous preoperative one week use of nitrofurantoin can significantly reduce the incidence of urinary sepsis. So the investigators assume that preoperative extended use time of prophylaxis antibiotic may reduce the incidence of urinary tract infection or urinary sepsis. This study uses a computerized random method. According to preoperative use of different antimicrobial drug or treatment, all patients are randomly divided into five groups, namely levofloxacin 3days group,levofloxacin 7days group, nitrofurantoin 3days group,nitrofurantoin 7days group and cefuroxime group.The levofloxacin group receives levofloxacin 0.5g, qd, po, the nitrofurantoin group was given oral nitrofurantoin 100mg, tid, po.to explore the better antibiotics types, medication timing and duration of treatment to prevent postoperative infection after minimally invasive upper tract lithotomy, so as to reduce the incidence of postoperative urinary tract infection or sepsis.

NCT ID: NCT02669342 Recruiting - Clinical trials for Urinary Tract Infections

Sharklet Catheter Study

Start date: August 2016
Phase: Phase 1
Study type: Interventional

The aim of this study is to determine if the Sharklet catheter, with its unique coating, reduces infections in participants, when compared to a standard catheter.

NCT ID: NCT02658903 Recruiting - Urinary Infections Clinical Trials

Prevention of Catheter Associated Lower Urinary Infections Using the Oxys Indwelling Catheter

Start date: January 2016
Phase: Phase 1
Study type: Interventional

The safety and efficacy of a urinary catheter designed to prevent catheter associated urinary infections is studied.

NCT ID: NCT02650518 Recruiting - Clinical trials for Catheter-Related Infections

Controlling Antimicrobial Use Through Reducing Unnecessary Treatment of Catheter Associated Urinary Tract Infections

CARCUTI
Start date: December 2015
Phase: Phase 2/Phase 3
Study type: Interventional

Hypothesis: A short course (3-5 days) of antibiotic therapy (experimental arm) is as safe and effective as a long course of antibiotic therapy for the treatment of catheter-associated urinary tract infections.

NCT ID: NCT02572895 Recruiting - Clinical trials for Urinary Tract Infections

Cranberry Extract and Urinary Infection Prevention: a Clinical Trial

PACCANN
Start date: August 2015
Phase: Phase 1
Study type: Interventional

The purpose of this clinical trial study is to assess, among young and sexually active women presenting recurrent urinary tract infection (UTIs), efficacy of an optimal dose of cranberry extract quantified and standardized to 37 mg/day of Proanthocyanidins (PACs), compared to a control dose quantified and standardized to 2 mg/day of PACs on mean number of new UTIs during a 6-month follow-up period.