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Urinary Stone clinical trials

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NCT ID: NCT06412900 Not yet recruiting - Urolithiasis Clinical Trials

Radiomics and Image Segmentation of Urinary Stones by Artificial Intelligence

RISUS_AI
Start date: May 15, 2024
Phase:
Study type: Observational [Patient Registry]

Kidney stone disease causes significant morbidity, and stones obstructing the ureter can have serious consequences. Imaging diagnostics with computed tomography (CT) are crucial for diagnosis, treatment selection, and follow-up. Segmentation of CT images can provide objective data on stone burden and signs of obstruction. Artificial intelligence (AI) can automate such segmentation but can also be used for the diagnosis of stone disease and obstruction. In this project, the aim is to investigate if: Manual segmentation of CT scans can provide more accurate information about kidney stone disease compared to conventional interpretation. AI segmentation yields valid results compared to manual segmentation. AI can detect ureteral stones and obstruction or predict spontaneous passage.

NCT ID: NCT06083051 Recruiting - Urinary Stone Clinical Trials

Differences in Postoperative Symptoms With Four Ureteral Stents

Start date: March 21, 2024
Phase: N/A
Study type: Interventional

This is a prospective randomized controlled trial designed to assess the differences in postoperative symptoms related to placement of a 6Fr Percuflex ureteral stents, 6Fr Tria ureteral stents, 4.8Fr Percuflex ureteral stents, and 4.8Fr Tria ureteral stents after ureteroscopy with laser lithotripsy for treatment of upper tract urinary stones. 272 participants will be enrolled and will be on study for up to approximately 10 weeks.

NCT ID: NCT05592457 Recruiting - Urinary Stone Clinical Trials

Role of Non-contrast MDCT in the Assessment of Upper Urinary Tract Calculi Post ESWL to Predict Its Success Rate

Start date: October 15, 2022
Phase:
Study type: Observational [Patient Registry]

Urinary stones are a common disease affecting one in 11 people . Their clinical presentation varies from being silent to severe loin pain owing to urinary obstruction. Currently, ESWL is the treatment of choice for most renal calculi ⩽30 mm, with success rates of 60-99%. Although many treatment options exist, ESWL has the advantages of simplicity and non-invasiveness. In contrast, failure of a first ESWL attempt requires a follow-up ESWL procedure, or an alternative procedure, both of which increase medical costs. Advancements in imaging have significantly contributed to this process. In the mid- 1990s, computed tomography (CT) began to replace intravenous urography (IVU), abdominal films (KUB), and ultrasound (US) in stone diagnosis. Studies demonstrated that CT had superior sensitivity and specificity for stone diagnosis compared to the aforementioned modalities. Now non-contrast multidetector CT (NC-MDCT) is the gold standard for the detection of urinary system calculi. CT is also clinically useful as it can show alternate renal and non-renal pathology if present. Many factors have been reported to predict ESWL outcome, such as skin-to-stone distance (SSD), stone size, stone location, multiplicity, the energy used, and Hounsfield Unit (HU) values measured by non-contrast computed tomography (NCCT).

NCT ID: NCT04924790 Recruiting - Covid19 Clinical Trials

The Effect of the COVID-19 on Patient Preferences and Decision Making for Obstructive Urinary Stone Interventions

Start date: September 1, 2021
Phase:
Study type: Observational

In this study, the investigators aim to evaluate the intervention preferences of patients with obstructive urinary stones who are suitable for operation during the COVID-19 pandemic. The secondary aim is to compare and evaluate the preferences compared to the pre-pandemic period and to gain a perspective on how the decision-making process has changed from the patient's point of view. Thus, by trying to understand how the COVID-19 epidemic affects the treatment choice decisions of patients, the investigators aim to determine how the state of anxiety changes these preferences.

NCT ID: NCT04846465 Recruiting - Urinary Stone Clinical Trials

Femoral Neck-shaft Angle in Sohag Population

NSA
Start date: September 14, 2021
Phase:
Study type: Observational

The femur or thigh bone is the strongest and longest bone of the body and about 45 cm long in an average man that means approximately one fourth of the height of individual. It has upper end, lower end and a cylindrical shaft. Upper end consists of head, neck. The neck is about 5 cm long, connects the head to the shaft and is directed upward, medially and slightly forward and making an angle about 125 with shaft but the angle is wider in children. The neck-shaft angle (NSA ) is defined as the angle formed by the neck axis and long axis of the shaft of femur.The knowledge of the neck shaft angle is valuable in the diagnosis and treatment of fracture of upper end of femur. The aim of the study is : 1. to evaluate the normal values of femoral neck-shaft angle 2. to detect factors that may affect this angle as age, and sex, in Egyptian adults from Sohag.

NCT ID: NCT04796792 Not yet recruiting - Urinary Calculi Clinical Trials

Ultrasound to Facilitate Stone Passage

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

This is a prospective, open-label, multi-center study to test the clinical feasibility of facilitating stone passage by the combination of breaking and repositioning stones with ultrasound, without the need for anesthesia.

NCT ID: NCT04697706 Completed - Urinary Stone Clinical Trials

Effect of a High Citrate Beverage on Urine Chemistry in Urinary Stone Disease

Start date: September 1, 2020
Phase: Early Phase 1
Study type: Interventional

This study will investigate the effect of a patented high citrate beverage on urine chemistry in patients with urinary stone disease (USD). It is a minimal risk study of an over-the-counter beverage called Moonstone, which is commercially available. This study is considered preparatory for the RO-1 and is not intended to produce a definitive outcome regarding kidney stones.

NCT ID: NCT04598971 Recruiting - Clinical trials for Urinary Tract Infections

Urine pH and Urinary Tract Infection

PHURINE
Start date: August 1, 2020
Phase:
Study type: Observational

Urinary tract infections (UTI) affect the urine pH and may lead to salt precipitation such as struvite. Bacteria with urease activity are known to alkalinise urine, but not much is known on how pH is changing over time during UTI. This study aims at following urine pH progression at the time of diagnosis of UTI and during the treatment phase. Description of the change in urine pH over time will help understanding the risk of struvite formation and potential timing of intervention.

NCT ID: NCT04594161 Completed - Kidney Diseases Clinical Trials

Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis

STONE
Start date: July 15, 2020
Phase: N/A
Study type: Interventional

To investigate the effectiveness of percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease (with either infection and/or pain and/or kidney function deterioration) caused by urolithiasis.

NCT ID: NCT04387617 Completed - Urinary Stone Clinical Trials

A Study to Assess the Effect of Cannabidiol Oil on Pain After Ureteroscopy for Kidney Stones

Start date: February 15, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine if CBD oil has any effect on decreasing postoperative pain control following ureteroscopy for urinary stone disease, and to determine if CBD oil has any effect in decreasing the amount of postoperative opioids (commonly used drug) used by patients after undergoing ureteroscopy for urinary stone disease.