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Urinary Incontinence, Urge clinical trials

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NCT ID: NCT01737918 Recruiting - Clinical trials for Surgical Treatment of Urge Incontinence

Treatment of Urge Urinary Incontinence in Women After Failure of Cesa or Vasa

URGE-II
Start date: January 2013
Phase: Phase 1/Phase 2
Study type: Interventional

Urge urinary incontinence can be a disorder caused by destroyed pelvic structures. We repaired the uteri-sacral ligaments (USL) by cesa or vasa. The study evaluates if solifenacin can lead to continence after surgery or if also the pubo-urethral ligaments (PUL) need to be repaired.

NCT ID: NCT01737411 Recruiting - Clinical trials for Urge Urinary Incontinence

Surgical vs. Medical Treatment of Urge Urinary Incontinence in Women

URGE-I
Start date: January 2013
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine if pelvic surgery can improve urge urinary incontinence in women more than standard medical treatment.

NCT ID: NCT01672190 Completed - Clinical trials for Urinary Incontinence

Lessening Incontinence by Learning Yoga

LILY
Start date: August 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the feasibility of recruiting women with urinary incontinence into a randomized controlled trial of a yoga therapy program.

NCT ID: NCT01644409 Completed - Overactive Bladder Clinical Trials

Urgent-SQ in Treatment of Overactive Bladder Syndrome: 9-yr Follow up

Start date: January 2012
Phase: N/A
Study type: Observational

Long term open label study on safety and durability of the Urgent-SQ tibial implant device for refractory overactive bladder syndrome (OAB).

NCT ID: NCT01619995 Completed - Clinical trials for Urge Urinary Incontinence

Brain Imaging Plus Urodynamics to Investigate the Brain's Control of the Bladder

NIRS/fBFB
Start date: August 2011
Phase: N/A
Study type: Observational

The goal of this project is to evaluate the applicability of non-invasive optical imaging for the measurement of brain function during investigation of the lower urinary tract.

NCT ID: NCT01559389 Completed - Clinical trials for Urge Urinary Incontinence

Incontinence & Intimate Partners: Assessing the Contribution of Treatment

IIMPACT
Start date: March 9, 2012
Phase: Phase 4
Study type: Interventional

Urge urinary incontinence (UUI) is a socially debilitating disease due to its inherently unpredictable nature and sometimes large volumes of urine loss. Women with UUI may experience anxiety over public episodes of incontinence and concerns about odor and, as a result, isolate themselves socially. This isolation affects both partners in the relationship and may be a source of discord. The impact of UUI also moves into personal relationships where fears or actual episodes of incontinence during physical intimacy, including but limited to intercourse, may result in limited interactions and changes in the relationship satisfaction for both partners. Few studies have examined the role of urinary incontinence, particularly UUI, in the dynamics of an intimate partner relationship and none have evaluated the impact of successful UUI treatment. The long-term goal of our research is to understand the social and emotional impact of pelvic floor disorders, particularly UUI, on the well-being of an intimate relationship. Ultimately, we aim to evaluate the role that successful treatment plays in the alleviation of discord in intimate partner relationships that are affected by UUI and other pelvic floor disorders. Our objective for this proposal is to characterize, using validated, quantifiable methods the quality of the relationship in couples affected by UUI and to identify the role that treatment plays in improving this relationship. Our central hypothesis is that UUI has a negative impact upon the emotional and physical well-being of a relationship and that effective treatment will result in improvement in areas of the relationship that have been detrimentally affected by UUI. Our rationale for this study is that an understanding of UUI in the context of a couple, particularly from the perspective of the male partner, will improve our ability to holistically treat UUI, thus improving patient outcomes and satisfaction.

NCT ID: NCT01512004 Completed - Overactive Bladder Clinical Trials

Propiverine Hydrochloride Extended-Release Capsule for Overactive Bladder

Start date: January 2010
Phase: Phase 3
Study type: Interventional

The purpose of this Phase III study is to evaluate the efficacy and safety of Propiverine Hydrochloride Extended-Release Capsule in the treatment of overactive bladder in Chinese population with urgent micturition, frequent micturition and/or urge urinary incontinence.

NCT ID: NCT01502956 Completed - Clinical trials for Urinary Incontinence, Urge

Refractory Overactive Bladder: Sacral NEuromodulation v. BoTulinum Toxin Assessment (ROSETTA)

ROSETTA
Start date: February 2012
Phase: Phase 3
Study type: Interventional

The purpose of this randomized, open-label, active-control trial is to compare the effectiveness of intra-detrusor botulinum toxin A (Botox A®, Allergan) versus sacral neuromodulation (InterStim®, Medtronic) for the treatment of refractory urge urinary incontinence. In addition, the study will evaluate select technical attributes of the interventions as well as the effect of these two interventions on other lower urinary tract and pelvic floor symptoms. Hypothesis: InterStim® therapy will result in a greater reduction in daily urge urinary incontinence episodes over the 6-month follow-up period as compared to Botox A® injection. A supplemental study investigates whether biological markers including those related to inflammation and connective tissue remodeling change following treatments with Botox A® and Interstim®.

NCT ID: NCT01470560 Completed - Clinical trials for Urinary Incontinence

Mindfulness-Based Stress Reduction Techniques and Yoga for Treatment of Urinary Urge Incontinence (MBSR-Yoga)

MBSR-Yoga
Start date: February 2011
Phase: N/A
Study type: Interventional

Many women experience the accidental loss of urine called urge incontinence or overactive bladder (OAB) incontinence. Women describe this as a sudden, strong desire to pass urine which results in leakage before reaching the toilet. The current usual treatments for urge incontinence include behavioral treatment, physical therapy, and medicines. Although these treatments have been found to be effective in research studies, they are less effective over time in general practice. Because medicines have side effects, many women stop them. The purpose of this study is to explore different treatments that may provide another option for women with urge incontinence that might be effective. This is an initial study to see if these treatments are at least as effective as the usual treatments. Hypothesis: Does Mind Based Stress Reduction(MBSR)(meditation practices)reduce urinary urge incontinence episodes?

NCT ID: NCT01464372 Terminated - Clinical trials for Urinary Incontinence, Urge

Electromagnetic Stimulation for the Treatment of Urge Urinary Incontinence and Overactive Bladder

ELEC STIM
Start date: October 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to collect data on the safety and efficacy of using an electrical field stimulation device, compared to a sham (placebo) device, to treat urinary urgency, urinary frequency and urge incontinence.