Urge Urinary Incontinence Clinical Trial
Official title:
Surgical vs. Medical Treatment of Urge Urinary Incontinence in Women
The purpose of this study is to determine if pelvic surgery can improve urge urinary incontinence in women more than standard medical treatment.
Urge Urinary Incontinence affects 30% of postmenopausal women. The etiology is unknown
therefore treatment is symptomatic. For that purpose the nerval stimulation of the bladder
muscle is interfered by several drugs, e.g. solifenacin.
We observed that the surgical repair of critical pelvic structures, i.e. the uteri-sacral
ligaments (USL) can restore continence in a considerable number of patients.
In this study the surgical treatment is compared with the solifenacin treatment. According
to outcome after three months patients who are still incontinent are referred to the
opposite treatment group.
Outcome will be differentiated in cure (primary aim) and improvement of symptoms (secondary
aim).
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment
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