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Urinary Incontinence, Stress clinical trials

View clinical trials related to Urinary Incontinence, Stress.

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NCT ID: NCT05677295 Recruiting - Clinical trials for Women With Stress Urinary Incontinence

Therapeutic Efficacy in Women With Stress Urinary Incontinence

Start date: April 18, 2023
Phase: Phase 3
Study type: Interventional

We will get the impact of duloxetine versus imipramine on therapeutic efficacy in women with SUI.

NCT ID: NCT05674045 Completed - Clinical trials for Stress Urinary Incontinence

A Phase 2, Randomized, Placebo-controlled, Double-blind Study of EG017 in Female Patients With Stress Urinary Incontinence

Start date: January 6, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether EG017 is safe and effective in the treatment of stress urinary incontinence in postmenopausal women.

NCT ID: NCT05670392 Not yet recruiting - Clinical trials for Stress Urinary Incontinence

Laser and High Intensity Tesla Magnetic Stimulation (HITS) for Stress Urinary Incontinence (SUI)

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

To investigate the efficacy of combined laser and HITS treatment for female stress urinary incontinence (SUI)

NCT ID: NCT05667012 Recruiting - Incontinence Stress Clinical Trials

Online Education Program in Sportswomen for the Prevention of Stress Urinary Incontinence

Start date: January 2, 2023
Phase: N/A
Study type: Interventional

Stress urinary incontinence (SUI) can be defined through its symptoms as the involuntary loss of urine when carrying out an activity or effort that implies an increase in intra-abdominal pressure (IAP). Perineal dysfunctions are a widespread problem among the sportswomen population. Therefore, a continuous exposure to exercises that entail a high intra-abdominal pressure such as that which occurs in high-impact sports in women. As seen in other studies in which pelvic floor educational programs were taught; advice and guidance focused on perineal health education helped participants improve knowledge, symptoms, and quality of life, as well as reduce the incidence of SUI. For these reasons, it is relevant to carry out a prevention and education program in the female population who play high-impact sports, since they have a high prevalence of SUI.

NCT ID: NCT05647070 Recruiting - Clinical trials for Stress Urinary Incontinence

Long-term Outcomes of Autologous Transobturator Rectus Fascia Sling for Treatment of Female Stress Urinary Incontinence

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Autologous transobturator sling placement is associated with excellent short-term results and can be performed on an outpatient basis in most cases, so long-term outcomes needs to be verified.

NCT ID: NCT05646745 Recruiting - Clinical trials for Stress Urinary Incontinence

Autologous Transobturator Fascia Lata Sling in Treatment of Female Stress Urinary Incontinence

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

To evaluate the outcome of autologous transobturator fascia lata sling for treatment of female stress urinary incontinence at Al-Azhar university hospitals.

NCT ID: NCT05635669 Recruiting - Clinical trials for Stress Urinary Incontinence

Optimized Acupuncture Treatment for Female Stress Urinary Incontinence

Start date: January 4, 2023
Phase: N/A
Study type: Interventional

This multicenter randomized controlled trial is designed to explore a relatively suitable application of acupoint combinations and to provide certain clinical evidence for the optimization of acupuncture treatment of female SUI.

NCT ID: NCT05635175 Not yet recruiting - Clinical trials for Women With Stress Urinary Incontinence

Effectiveness of a Hip Abductor Training in Women With Stress Urinary Incontinence

PROTOGLUT
Start date: May 2023
Phase: N/A
Study type: Interventional

Urinary incontinence (UI) is estimated to affect 25% à 45 % women all over the world. UI is associated with a poor Quality of life, with a strong level of certainty. Stress urinary incontinence (SUI) is the second more prevalent type of UI . First-line treatment for SUI is conservative, non-drug and non-surgical treatment. Among these techniques, physiotherapist-supervised pelvic floor muscle (PFM) training (PFMT) as a first-line treatment; however, only half of women with SUI are cured with PFMT. Brain imaging shows that PFMs (involved in continence mechanisms) and gluteal muscles can activate the same cortical region. This synergy is found if the gluteal muscles are voluntarily activated, but not if the PFMs are volontary activated alone . In women, hip abductor physiotherapy is a common practice which has already been the subject of a very extensive literature and has largely shown its effectiveness in the quality of lumbo-pelvic control, balance, quality of life and risk of fall prevention. This rehabilitation is based on exercises that induce solicitation of the hip abductors by synergistic reflex activation during a range of well-known exercises. Recent work has shown the effect of hip abductors on the activation of the PFMs . Until today, there is no literature evaluating the effectiveness of a hip abductors training program without associated voluntary contraction of the PFMs (PPM) on UI. The hypothesis of this work will be to demonstrate that a complementary training focused on the hip abductor, complementary to concomitant PFMT, would benefit from a more significant improvement in continence, and also in physical abilities and quality of life. Because balance seems involved in UI, we therefore propose to to observe the effects on the frontal balance of the pelvis. As the investigators have already done in previous studies, to identifying factors that predict the success of our interventions, investiagtors have planned to evaluate the observance and adherence of our patients .Complementary, the investigators planned to evaluate the effect of both intervention on pelvic floor muscles and hip abductors strength and endurance, pelvic organ prolapse symptoms and quality of life. For this objective, the investigators intend to compare two randomized parallel groups: Group A follow a 12 sessions supervised PFMT + home based PFMs exercices. Group B follow a 12 sessions supervised PFMT + home based hip abductor exercices.

NCT ID: NCT05629481 Recruiting - Clinical trials for Stress Urinary Incontinence

A Study of Fractional Carbon Dioxide Laser Treatment for Female Stress Urinary Incontinence

Start date: April 20, 2022
Phase: N/A
Study type: Interventional

Urinary incontinence (UI) is a common disease that refers to involuntary loss of urine. The prevalence of female UI varies widely across different studies, mostly ranging from 25-40%. Stress urinary incontinence (SUI) is the most common type of UI. SUI is defined as involuntary loss of urine when abdominal pressure increases suddenly such as coughing or sneezing. SUI affects women's quality of life seriously, causing psychological problems such as anxiety and depression, even socialization difficulties. There are many treatment options for female SUI, including non-surgical and surgical interventions. Clinicians and patients need a highly effective and low-risk therapy urgently, thus energy-based therapies were born on demand. This study aims to demonstrate the efficacy and safety of the fractional CO2 laser in the treatment of female SUI, as well as its impact on women's quality of life.

NCT ID: NCT05627726 Not yet recruiting - Clinical trials for Stress Urinary Incontinence

Effectiveness and Cost-effectiveness of PelviSense, a Novel Biofeedback Device for Stress Urinary Incontinence in Women

Start date: July 1, 2024
Phase: N/A
Study type: Interventional

Aims: (1) Investigate the efficacy of PelviSense-assisted PFMT compared with PFMT alone for improving SUI symptom severity in women; (2) Compare the cost-effectiveness of the PelviSense device against PFMT alone for treating SUI in women; (3) Explore the views of women regarding the use of the PelviSense device as an adjunct to PFMT and the impacts of the PelviSense device on their lives and well-being. Design and subjects: A sequential, embedded, experimental mixed-methods design, including a randomised controlled trial (RCT) and semi-structured focus groups, will be conducted alongside an economic evaluation. The proposed study will include 142 women with SUI or stress-predominant mixed urinary incontinence. Interventions: Women will be randomly allocated to one of two groups (PelviSense or PFMT alone [control]). The PelviSense group will perform PFMT with assistance from the PelviSense device, and the control group will perform PFMT without biofeedback (i.e., PFMT alone). Outcome measures: International Consultation on Incontinence Questionnaire-Short Form, one-hour pad test, Modified Oxford Scale, EQ-5D-5L, and electronic cost diary. Data analysis and expected results: Statistical analysis will be conducted using analysis of covariance. The PelviSense group is expected to report significant improvements in primary and secondary outcomes compared with the PFMT alone group. The PelviSense group will yield cost savings and result in lower health care utility compared with the PFMT alone group.