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Urinary Bladder, Overactive clinical trials

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NCT ID: NCT03817931 Completed - Dementia Clinical Trials

Higher Neural Changes Following Anticholinergic, Beta 3 Agonist, or Placebo in Patients With Overactive Bladder

Start date: August 5, 2019
Phase: Phase 4
Study type: Interventional

Women presenting with overactive bladder symptoms will be randomized to one of 3 arms (anticholinergic, beta-3 agonist, placebo). They will undergo baseline cognitive testing, functional MRI of the brain. Cognitive testing and functional MRI will be repeated after taking their double blinded intervention for 30 days.

NCT ID: NCT03807024 Completed - Clinical trials for Urinary Bladder, Overactive

Age-specific Prevalence and Comparisons of UDS and Bladder Diary Between OAB-wet and -Dry Women

Start date: July 1, 2009
Phase:
Study type: Observational

The knowledge of the age-specific prevalence of overactive bladder syndrome (OAB)-wet and -dry women is important for understanding the impact of aging on OAB. Thus, our aim is to describe clinically differences between OAB-wet and -dry women.

NCT ID: NCT03801239 Completed - Clinical trials for Urinary Incontinence

Reliability of Polish-Version Overactive Bladder Syndrom Scores (OABSS)

Start date: June 1, 2017
Phase:
Study type: Observational

The aim of this study was to develop and assess the effectiveness of a Polish version of OABSS and to correlate the OABSS with urodynamic study results and UDI-6, IIQ-7 questionnaires

NCT ID: NCT03750604 Completed - Urologic Diseases Clinical Trials

Central Obesity in Cases of OAB

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Obesity is not a homogeneous condition and that the regional distribution of adipose tissue is important to understanding the relation of obesity to disturbances in glucose and lipid metabolism. Central abdominal fat is composed of abdominal subcutaneous fat and visceral fat. Regional distribution appears to be an important indicator for metabolic alterations since an inconstant correlation between body mass index (BMI) and these disturbances have been found. Visceral obesity is associated with increased adipocytokine production, proinflammatory activity, deterioration of insulin sensitivity, increased risk of developing diabetes, "high-triglyceride/low-HDL cholesterol dyslipidemia," hypertension and atherosclerosis. It might be more precise to divide central abdominal fat into subcutaneous(S) and visceral (V) fat surface area and volume and even ratio (S/V); risk factors for cardiovascular disease, particularly those related to glucose and lipid metabolism and hypertension, being>0.4; with evaluation of visceral fat functionality by visceral adiposity index (VAI) with integration with lipid profile. Adding bladder wall thickness with perivesical fat as a factor may impair bladder function and contribute to dysregulation. The data on the association between central adiposity with OAB symptoms and Urodynamics is not mature.

NCT ID: NCT03662893 Completed - Overactive Bladder Clinical Trials

Behavioural Therapy With Checklist for Overactive Bladder

Start date: January 1, 2015
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the efficiency of this newly-established checklist for overactive bladder (OAB) and whether determinate to adherence and persistence rate of combination of behavioural therapy and anticholinergic medications in patients with OAB.

NCT ID: NCT03655054 Completed - Overactive Bladder Clinical Trials

eCoin for OAB Feasibility Follow-on Study

Start date: March 13, 2019
Phase: N/A
Study type: Interventional

This trial is a prospective, multicenter, single-arm follow-on study will evaluate the safety and effectiveness of eCoinTM tibial nerve stimulation in subjects with urgency urinary incontinence (UUI) as defined by the American Urological Association (30). The follow-on study will evaluate changes from baseline in OAB symptoms as measured by voiding diaries and patient-reported outcomes through 24 weeks of eCoinTM therapy (which is the same as 28 weeks from study device reimplantation).

NCT ID: NCT03643380 Completed - Overactive Bladder Clinical Trials

Acute Study to Evaluate a Novel Implantable Midfield Powered Device in Humans With Urinary Incontinence

Start date: August 17, 2017
Phase: Phase 1
Study type: Interventional

A pre-market, prospective, non-randomized acute feasibility study for the treatment of patients with urinary incontinence (UI) as a consequence of urinary incontinence.

NCT ID: NCT03625843 Completed - Overactive Bladder Clinical Trials

Mindfulness Exercises to Reduce Anxiety and Pain During Urodynamic Testing

Start date: September 29, 2016
Phase: N/A
Study type: Interventional

In this pilot study the investigators attempt to answer the question, does mindfulness exercises before urodynamic testing reduce patient's perception of anxiety or pain?

NCT ID: NCT03625492 Completed - Overactive Bladder Clinical Trials

Fluids Affecting Bladder Urgency and Lower Urinary Symptoms

FABULUS
Start date: August 7, 2018
Phase: N/A
Study type: Interventional

This study evaluates whether eliminating certain ingredients (caffeine, alcohol, artificial sweeteners, acidic juices) consumed in beverages reduces bladder symptoms of urinary frequency and urgency. Women with overactive bladder will be recruited. Half of these women will receive instructions to replace beverages containing these ingredients with beverages such as water or milk. The other half of participants will receive instructions on following the United States Department of Agriculture guidelines on healthy eating.

NCT ID: NCT03602508 Completed - Clinical trials for Overactive Bladder (OAB)

Treatment Persistence Among Patients With Overactive Bladder: A Retrospective Secondary Data Analysis in Asia Oceania

Start date: July 20, 2018
Phase:
Study type: Observational

The purpose of this study is to descriptively evaluate the persistence among adults treated with mirabegron or antimuscarinics in Australia, South Korea and Taiwan. This study will also assess the persistence to the overall Overactive bladder (OAB) treatments of a patient, regardless of treatment discontinuation or switch to other OAB medications.