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Urge Incontinence clinical trials

View clinical trials related to Urge Incontinence.

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NCT ID: NCT05099419 Recruiting - Overactive Bladder Clinical Trials

Repetitive Transcranial Magnetic Stimulation in Women With Overactive Bladder With Urgency Incontinence

Start date: October 28, 2021
Phase: Early Phase 1
Study type: Interventional

Overactive bladder (OAB) affects an estimated 16-30% of women in the US and urgency urinary incontinence (UUI) affects 7-11% of women with OAB. It is known that repetitive transcranial magnetic stimulation (rTMS) over the supplementary motor area (SMA) can modulate the pelvic floor muscle activity with potential benefits for various urologic conditions. The goal of this study is to assess feasibility of rTMS as a treatment option for OAB with UUI by determining which rTMS frequency is most effective in targeting sensory components of OAB, namely urinary urgency, and also in targeting the brain network known to be involved in OAB.

NCT ID: NCT05094414 Recruiting - Quality of Life Clinical Trials

Using Oral Valacyclovir to Treat Patients With Refractory IC/BPS

VARIC
Start date: July 1, 2021
Phase: Phase 1
Study type: Interventional

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a collective term referring to disorders which is characterized by lower urinary tract symptoms, including bladder pain/discomfort, frequent urination without evidence of bacterial infection. The etiology of IC/BPS is still uncertain, and most current treatment for IC/BPS are only symptoms control. Our previous study revealed Epstein-Barr virus (EBV) infection presented in the IC/BPS bladders and involved the pathogenesis. Hence, using anti-viral medication valacyclovir for the patients with IC/BPS might have clinical efficacy.

NCT ID: NCT05013593 Completed - Overactive Bladder Clinical Trials

Red Clover Isoflavones in Postmenopausal Women With Urge Urinary Incontinence and Overactive Bladder

Start date: July 15, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effect of red clover isoflavones in postmenopausal women with and without urge urinary incontinence and overactive bladder

NCT ID: NCT04936464 Active, not recruiting - Overactive Bladder Clinical Trials

Transcutaneous Tibial Nerve Stimulation for Urgency Urinary Incontinence

TTeNS
Start date: September 20, 2021
Phase: N/A
Study type: Interventional

This is a single-center, double-blinded, randomized controlled trial evaluating the efficacy of TTNS versus a sham intervention. Both interventions will be performed by participants in their homes after standardized instruction. The primary outcome is a comparison of the mean change in OAB-q scores before and after treatment between the intervention and control groups. Changes in the number of urgency incontinence episodes and an estimation of cost effectiveness will additionally be measured. Intention to treat analysis will be performed.

NCT ID: NCT04853849 Recruiting - Overactive Bladder Clinical Trials

Treatment of Overactive Bladder With a Digital Conversational Agent: the MOTIVATION Study

MOTIVATION
Start date: August 26, 2021
Phase:
Study type: Observational

This is a proof of concept study for a digital therapeutic designed to provide first-line behavioral modification therapy for overactive bladder.

NCT ID: NCT04752709 Recruiting - Urge Incontinence Clinical Trials

Efficacy of Surface Electrical Stimulation for Urge Urinary Incontinence in Women

Start date: November 19, 2020
Phase: N/A
Study type: Interventional

The purpose of this research is to evaluate the effectiveness of the ELITONE-UUI electrical muscle stimulation device on treating urge incontinence. The aim of the device is to stimulate the pelvic floor muscles and surrounding structures to improve urinary incontinence.

NCT ID: NCT04727983 Completed - Urge Incontinence Clinical Trials

Effects of External Neuromuscular Electrical Stimulation in Women With Urgency Urinary Incontinence

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

To reveal the effects of Neuromuscular Electrical Stimulation (NMES) applied over the thigh on incontinence symptoms, pelvic floor muscle function, bladder function, quality of life and sexual function in women with urge urinary incontinence (UUI) symptoms. Our goal is to contribute to the literature on electrical stimulation (ES) applications used in UUI treatment. Female patients aged 18-65 years with UUI symptoms will be included in the study. Patients will be divided into 2 groups randomly. The first group will be given Neuromuscular Electrical Stimulation (NMES) and lifestyle suggestions (LSS) (NMES group). The second group will be given sham NMES in addition to LSS (SHAM ES group). Information about bladder irritants, voiding posture and behavior, weight control and pelvic floor muscle training will be provided in the LSS. ES applications will be performed 3 days a week for 30 minutes per session for 8 weeks. All participants will be evaluated pretreatment, after the 4th week and posttreatment. Pelvic floor muscle function will evulate with the Modified Oxford Scale. In addition, women's bladder function with the urinary diary for 3 days, incontinence symptoms with the International Incontinence Consultation Questionnaire-Short Form (ICIQ-SF) and the Coital Incontinence Score (CIS), quality of life with the King Health Questionnaire (KHQ) and Sexual Function will be evaluated with Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12). At the end of the 8th week, both the Subjective perception of improvement and treatment satisfaction of the patients will be questioned

NCT ID: NCT04619238 Completed - Clinical trials for Urinary Incontinence

Reliability of KHQ and ICIQ-SF in Assessing Urinary Incontinence Effects in Polish Women

Start date: June 1, 2017
Phase:
Study type: Observational

The aim of this study was to assess the psychometric properties of KHQ and ICIQ-SF in polish women.

NCT ID: NCT04562090 Completed - Urge Incontinence Clinical Trials

A Study With Mirabegron 50 mg and 25 mg in Chinese Participants With Overactive Bladder

Start date: January 6, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study was to evaluate the efficacy of mirabegron for the treatment of overactive bladder (OAB) in Chinese participants. This study also evaluated the safety of mirabegron for the treatment of OAB in Chinese participants, evaluated other efficacy variables of mirabegron for the treatment of OAB and explored different mirabegron starting doses.

NCT ID: NCT04527445 Not yet recruiting - Overactive Bladder Clinical Trials

Fluoroscopy Radiation Reduction During Sacral Neuromodulation Lead Placement

Start date: June 30, 2024
Phase: N/A
Study type: Interventional

Fluoroscopy is performed when placing a lead during a sacral neuromodulation procedure. During lead placement, subjects will receive either conventional or experimental fluoroscopic settings. The radiation exposure will be compared between the two groups.