Urolithiasis Clinical Trial
Official title:
Efectividad de la Tamsulosina Como Tratamiento Adyuvante Previo a Ureterolitotomia Endoscopica
This a study aiming to compare treatment with tamsulosin versus placebo in patients undergoing endoscopic treatment for urolithiasis. The main outcome is the rate of stone free patients.
Endoscopic treatment of urolithiasis has increased during the last several years. Adrenergic
receptors have been described mainly in the distal ureter. Blockage of adrenergic receptors
has been associated to a decrease in ureteral resistance. In this study the investigators
hypothesized that alpha blockers are associated to a decrease in ureteral resistance with an
increase in successful endoscopic management of urolithiasis.
Only patients with urolithiasis undergoing to endoscopic treatment are offered to
participate. Patients are randomized between placebo arm or tamsulosin 0.4 mg/day.
Demographic characteristics, stones characteristics and information related to surgery are
recorded. Main study outcome is stone free rate and successful insertion of semirigid
ureteroscope 8,0 - 9,8 Fr. All patients are follow-up for 30 days after surgery.
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