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Clinical Trial Summary

Several studies investigated the effectiveness of Gabapentin in Uremic Pruritus (UP). No previous studies investigated the use of fexofenadine in UP. The aim of this trial is to assess the safety and possible efficacy of fexofenadine in patients with UP.


Clinical Trial Description

A randomized controlled single center parallel study, that will recruit 60 participants with end stage renal disease (ESRD) on regular hemodialysis (RHD) with uremic pruritus (UP). Patients will be randomized to either Fexofenadine (60 mg orally once daily), or Gabapentin (100 mg orally after each dialysis session, "thrice weekly", with titration according to response to 100 mg orally once daily). Participants will continue treatment for 3 months. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06466421
Study type Interventional
Source Tanta University
Contact Mohamed I Elfalaha, PharmD
Phone +201020576299
Email Phmoehab@gmail.com
Status Not yet recruiting
Phase Phase 4
Start date July 1, 2024
Completion date December 20, 2024

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