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Evaluate the Potential of Montelukast to Prevent Nasal Symptomatology During Colds

Upper Respiratory Infection Clinical Trial

Official title:
A Pilot Study to Evaluate the Potential of Montelukast to Prevent the Development of Nasal Symptomatology During Natural Viral Upper Respiratory Infections

Clinical Trial Summary

Assesses the efficacy of treatment with montelukast 10 mg PO QD x 5 days versus placebo for the treatment of viral-induced upper respiratory infection in healthy adults aged 18-50 years.

Clinical Trial Description

This is a randomized double-blinded placebo controlled trial to assess the efficacy of treatment with montelukast 10 mg PO QD x 5 days versus placebo for the treatment of viral-induced upper respiratory infection in healthy adults aged 18-50 years. All subjects complete daily assessments of cold symptoms, nasal clearance rates and secretion rates during each day of the study. Phlebotomy is performed once for the determination of cytokine genotyping and allergy skin testing is performed once for the assessment of atopy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00189475
Study type Interventional
Source West Penn Allegheny Health System
Contact
Status Completed
Phase Phase 4
Start date October 2003
Completion date July 2007
View Details
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