Astral VAPS AutoEPAP Clinical Trial

Status Completed

Clinical Trial Summary

Patients with chronic respiratory failure such as those associated with Chronic Obstructive Pulmonary Disease (COPD), Obesity Hypoventilation Syndrome (OHS), Obstructive Sleep Apnea (OSA) or Neuromuscular Disease (NMD) are increasingly managed with domiciliary non-invasive positive pressure ventilation (NIPPV). The aim of this study is to now compare the Automatic Expiratory Positive Airway Pressure (AutoEPAP) algorithm with a fixed manual EPAP in iVAPS mode on an Astral mixed mode ventilator. It is proposed that the automatic settings of AutoEPAP will be as effective at managing respiratory failure and upper airway obstruction (UAO) as manual EPAP on the Astral device. Specifically demonstrating that the AutoEPAP function is as effective at treating UAO as manual EPAP.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02683772
Study type	Interventional
Source	ResMed
Contact
Status	Completed
Phase	Phase 3
Start date	April 15, 2016
Completion date	July 6, 2017

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03909854` - Pragmatic Investigation of Volume Targeted Ventilation-1	N/A
Recruiting	`NCT03662438` - HOPE (Home-based Oxygen [Portable] and Exercise) for Patients on Long Term Oxygen Therapy (LTOT)	N/A
Recruiting	`NCT05308719` - Nasal Oxygen Therapy After Cardiac Surgery	N/A
Recruiting	`NCT05535543` - Change in the Phase III Slope of the Volumetric Capnography by Prone Positioning in Acute Respiratory Distress Syndrome
Completed	`NCT04030208` - Evaluating Safety and Efficacy of Umbulizer in Patients Requiring Intermittent Positive Pressure Ventilation	N/A
Recruiting	`NCT04542096` - Real Time Evaluation of Dynamic Changes of the Lungs During Respiratory Support of VLBW Neonates Using EIT
Recruiting	`NCT04668313` - COVID-19 Advanced Respiratory Physiology (CARP) Study
Recruiting	`NCT05883137` - High-flow Nasal Oxygenation for Apnoeic Oxygenation During Intubation of the Critically Ill
Completed	`NCT04505592` - Tenecteplase in Patients With COVID-19	Phase 2
Completed	`NCT03943914` - Early Non-invasive Ventilation and High-flow Nasal Oxygen Therapy for Preventing Delayed Respiratory Failure in Hypoxemic Blunt Chest Trauma Patients.	N/A
Active, not recruiting	`NCT03472768` - The Impact of Age-dependent Haptoglobin Deficiency on Plasma Free Hemoglobin Levels During Extracorporeal Membrane Oxygenation Support
Not yet recruiting	`NCT04538469` - Absent Visitors: The Wider Implications of COVID-19 on Non-COVID Cardiothoracic ICU Patients, Relatives and Staff
Not yet recruiting	`NCT02542423` - Endocan Predictive Value in Postcardiac Surgery Acute Respiratory Failure.	N/A
Completed	`NCT02265198` - Relationship of Pulmonary Contusion to Pulmonary Inflammation and Incidence of Acute Respiratory Distress Syndrome	N/A
Completed	`NCT01885442` - TryCYCLE: A Pilot Study of Early In-bed Leg Cycle Ergometry in Mechanically Ventilated Patients	N/A
Completed	`NCT02105298` - Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)	N/A
Completed	`NCT01659268` - Performance of Baccalaureate Nursing Students in Insertion of Laryngeal Mask: a Trial in Mannequins	N/A
Completed	`NCT02814994` - Respiratory System Compliance Guided VT in Moderate to Severe ARDS Patients	N/A
Completed	`NCT01204281` - Proportional Assist Ventilation (PAV) in Early Stage of Critically Ill Patients	Phase 4
Completed	`NCT01249794` - Non Invasive Ventilation After Cardiac Surgery	N/A