Clinical Trials Logo

Clinical Trial Summary

This study aims to initially utilize machine learning on pan-cancer DNA methylation data from public databases to construct a DNA methylation classification model (PaCIFiC-CUP, pan-cancer integrated fingerprinting classifier of CUP) for diagnosing various types of cancer, particularly the primary site of cancer of unknown primary. The goal is to achieve diagnosis of cancer pathology type by analyzing the DNA methylation patterns of cancer specimens, thereby guiding subsequent precision treatment for cancer.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06140992
Study type Observational
Source Sun Yat-sen University
Contact Yiyang Zhang
Phone +8615652797092
Email zhangyy@sysucc.org.cn
Status Recruiting
Phase
Start date July 1, 2023
Completion date December 31, 2025

See also
  Status Clinical Trial Phase
Completed NCT03642574 - Preimplantation DNA Methylation Test (PIMT) in ART N/A
Completed NCT03787849 - Epigenetics in PostOperative Pediatric Emergence Delirium N/A
Recruiting NCT05442125 - First Live Birth Rate With eSET After Preimplantation Methylome Screening (PIMS) Versus Conventional In-vitro Fertilization N/A
Recruiting NCT05624827 - The Role of FAM19A4 and Hsa-mir-124 Methylation in Predicting Prognosis of Untreated Cervical Intraepithelial Neoplasia 2 (CIN 2) N/A
Completed NCT05085847 - Effects of Mindfulness-based Intervention on Epigenetic Mechanisms, Cognition Function, Stress Response, and Well-being N/A
Recruiting NCT04646954 - DNA Methylation Testing for the Screening of Uterine Cervical Lesion Phase 3
Recruiting NCT04651946 - Cell-free DNA Methylation for Epithelial Ovarian Cancer Phase 2
Recruiting NCT03961191 - DNA Methylation for Screening Uterine Cervical Lesions: A Case-control Study
Not yet recruiting NCT05779904 - Methylation, mIcrobiome, NUtritional sTatus, and dEvelopment of Stunted Children
Recruiting NCT05791149 - Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity N/A
Recruiting NCT05801276 - ctDNA Methylation for Detecting Ovarian Cancer
Recruiting NCT05801263 - ctDNA Methylation for Epithelial Ovarian Cancer
Recruiting NCT05290415 - Host DNA Methylation for Endometrial Cancer Screening
Recruiting NCT05290922 - DNA CDO1 and CELF4 Methylation for Endometrial Cancer Screening
Recruiting NCT05290428 - DNA PAX1 and JAM3 Methylation for Cervical Cancer Screening
Recruiting NCT03960879 - DNA Methylation for Screening Uterine Cervical Lesions
Recruiting NCT05737953 - Construction of Molecular Diagnostic Marker Model for Pancreatic Cystic Tumors Based on Pancreatic Cystic Fluid Samples
Completed NCT02032628 - DNA Methylation and Cancer Prevention: Duration and Intensity of Exercise N/A
Completed NCT04568512 - DNA Methylation Biomarker for Diagnosis of Cholangiocarcinoma in Patients With Bile Duct Stricture N/A
Completed NCT03227003 - DNA Methylation and 1-C Metabolism Nutrient Intake N/A