Clinical Trials Logo
  1. Home
  2. Unexplained Infertility
  3. NCT02349750

Endometrial Scratch Injury in Women With Unexplained Infertility Undergoing IUI

Unexplained Infertility Clinical Trial

Official title:
Endometrial Scratch Injury Induced Higher Pregnancy Rate for Women With Unexplained Infertility Undergoing IUI With Ovarian Stimulation

Clinical Trial Summary

The study included 154 infertile women Patients received 100 mg of oral clomiphene citrate for five days starting on day 3 of the menstrual cycle, followed by daily injection of 150 IU of hMG and when more than two dominant follicles reached a diameter of 17 mm 5,000 IU of hCG was injected intramuscularly. Patients were randomly allocated into two equal groups: Group C received IUI without ESI and Group S had ESI using No.8 neonatal feeding tube and after 24 to 36 hours, IUI was performed. Successful pregnancy was con-firmed by ultrasound and patients had failed trial underwent another trial of IUI for a maximum of three trials.

Clinical Trial Description

The study included 154 infertile women with mean duration of infertility of 3.9±0.4 years. Patients received 100 mg of oral clomiphene citrate for five days starting on day 3 of the menstrual cycle, followed by daily injection of 150 IU of hMG and when more than two dominant follicles reached a diameter of 17 mm 5,000 IU of hCG was injected intramuscularly. Patients were randomly allocated into two equal groups: Group C received IUI without ESI and Group S had ESI using No.8 neonatal feeding tube and after 24 to 36 hours, IUI was performed. Successful pregnancy was con-firmed by ultrasound and patients had failed trial underwent another trial of IUI for a maximum of three trials. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02349750
Study type Interventional
Source Cairo University
Contact
Status Completed
Phase N/A
Start date January 2010
Completion date January 2013
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04169451 - IUI With Letrozole Versus in Natural Cycle N/A
Completed NCT01672801 - Nimodipine to Prevent LH Surge During Ovulation Induction: Blinded Placebo-controlled RCT N/A
Completed NCT01232465 - Impact of Sperm DNA Integrity on In Vitro Cycles N/A
Not yet recruiting NCT01237535 - Luteal Phase Support With Progesterone Versus Estrogen and Progesterone on Pregnancy Rates Phase 4
Completed NCT02272439 - Endocrine Disrupting Chemicals: Potential Effects on Male and Female Reproductive Health in Saskatchewan N/A
Terminated NCT00650754 - Study of Oral Dehydroepiandrosterone(DHEA) to Treat Previously Unexplained Infertility Phase 2/Phase 3
Recruiting NCT04754243 - New Protocol in Unexplained Infertility Phase 4
Completed NCT03018314 - Serum Kisspeptin Levels in Infertile Women N/A
Completed NCT02488434 - The Effects of Using Fertile Chip in Sperm Selection for Intracytoplasmic Sperm Injection in Unexplained Infertility Phase 3
Completed NCT02739516 - Dual FSH/HCG Trigger in Letrozole Stimulated Intrauterine Insemination Cycles in Women With Unexplained Infertility Phase 3
Completed NCT02628756 - Endometrial Injury in Women With Unexplained Infertility N/A
Completed NCT01044862 - Assessment of Multiple Intrauterine Gestations From Ovarian Stimulation Phase 3
Recruiting NCT03386552 - A Study of Lidocaine Pertubation as a Treatment for Unexplained Infertility Phase 2
Completed NCT04465045 - Unexplained Infertility Treated by Hysteroscopy-laparoscopy
Completed NCT03461601 - Uterine Flushing With Human Chorionic Gonadotrophin and Unexplained Infertility N/A
Completed NCT01859520 - Swim up and Gradient Methods Used in Assisted Reproduction Techniques on DNA Fragmentation of Spermatozoa N/A
Active, not recruiting NCT03828786 - Uterine Scratching in Intra-Uterine Insemination N/A
Completed NCT03397693 - Assessment of Endometrial Thickness & Subendometrial Perfusion by 3D Power Doppler in Women With Unexplained Infertility and PCOS.
Withdrawn NCT04955574 - Probiotic and Antibiotic Therapies in Women With Unexplained Infertility Phase 2
Not yet recruiting NCT03398993 - Effect of Endometrial Injury in Couples With Unexplained Infertility N/A