Graft-Versus-Host Disease Clinical Trial
Official title:
A Multi-Center, Phase II, Randomized Double-Blind Trial to Evaluate the Efficacy and Safety of Photobiomodulation for the Treatment of Oral Chronic Graft-Versus-Host Disease After Allogeneic Stem Cell Transplantation (the LIGHT Trial)
The purpose of this study is to find out whether photobiomodulation/PBM therapy using the Thor LX2.3 therapy system is a safe and effective treatment for oral Graft-Versus-Host Disease/GVHD.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
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Minitransplants With HLA-matched Donors : Comparison Between 2 GVHD Prophylaxis Regimens
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Phase 2 | |
| Not yet recruiting |
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Allogeneic Mesenchymal Stem Cell for Graft-Versus-Host Disease Treatment
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Phase 1/Phase 2 | |
| Completed |
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Randomized Trial Comparing Sirolimus and Tacrolimus Versus Cyclosporine and Methotrexate as Graft-versus-host Disease (GVHD) Prophylaxis After Allogeneic Stem Cell Transplantation
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Phase 3 | |
| Completed |
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Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTX
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N/A | |
| Active, not recruiting |
NCT04503616 -
Cyclophosphamide, Abatacept, and Tacrolimus for GvHD Prevention
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Phase 1/Phase 2 | |
| Terminated |
NCT02080195 -
Nonmyeloablative Conditioning and Transplantation for Patients With Refractory Systemic Lupus Erythematosus (SLE)
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Phase 1/Phase 2 | |
| Completed |
NCT02193880 -
Safety of Post-transplant Alpha-beta Depleted T-cell Infusion Following Haploidentical Stem Cell Transplant (Haplo SCT)
|
N/A | |
| Completed |
NCT02942173 -
CD45RA Depleted T-cell Infusion for Prevention of Infections After TCRab/CD19-depleted Allo-HSCT
|
Phase 2/Phase 3 | |
| Completed |
NCT02145403 -
Phase 1/2 Study of Carfilzomib for the Prevention of Relapse and GVHD in Allo-HCT for Hematologic Malignancies
|
Phase 1/Phase 2 | |
| Recruiting |
NCT01941394 -
Mesenchymal Stem Cells Infusion for aGVHD Prophylaxis Transplantation
|
Phase 2 | |
| Completed |
NCT00141713 -
The Use of Etanercept (Enbrel®) in the Treatment of Acute Graft-Versus-Host Disease
|
Phase 2 | |
| Recruiting |
NCT01991301 -
Carfilzomib for the Prevention of Graft Versus Host Disease
|
Phase 1 | |
| Completed |
NCT00408928 -
Study on the Safety and Effectiveness of VELCADE® in the Treatment of Graft-Versus-Host Disease
|
Phase 2 | |
| Completed |
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Bone Marrow Stromal Cell Infusions for Stem Cell Transplant Complications
|
Phase 1 | |
| Completed |
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Phase 1 | |
| Completed |
NCT02342613 -
Adoptive Immunotherapy With Activated Marrow Infiltrating Lymphocytes and Cyclophosphamide Graft-Versus-Host Disease Prophylaxis in Patients With Relapse of Hematologic Malignancies After Allogeneic Hematopoietic Cell Transplantation
|
Phase 1 | |
| Recruiting |
NCT06423131 -
Prospective Clinical Trial for Children With TCRαβ Depleted vs Traditional Haplo Identicle HSCT
|
N/A | |
| Completed |
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Prevention of Ocular Graft-Versus-Host Disease With Topical Cyclosporine in Recipients of Allogeneic HSCT
|
Phase 2 | |
| Completed |
NCT01369914 -
The Natural History of Graft-Versus-Host Disease in the Eyes
|
||
| Completed |
NCT00806728 -
Study of MEDI-507 in With Steroid-Resistant Acute Graft-Versus-Host Disease
|
Phase 1 |