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Efficacy of Mesalazine Combined With Biologics in the Treatment of Moderate to Severe Ulcerative Colitis

Ulcerative Colitis Clinical Trial

Official title:
Efficacy of Mesalazine Combined With Biologics in the Treatment of Moderate to Severe Ulcerative Colitis: a Multicenter, Prospective, Randomized, Controlled Clinical Study

Clinical Trial Summary

Endocopic remission rates of moderate to severe ulcerative colitis are low. Biologics including Vedolizumab, infliximab, and adalimumab are effective in induction and maintainence of ulcerative colitis. The role of 5-ASA in promoting a higher rate of endocsopic remission is unclear. We aim to evaluate the efficacy of combination of 5-ASA and biologics in treating ulcerative colitis.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05205603
Study type Interventional
Source Sixth Affiliated Hospital, Sun Yat-sen University
Contact Min Zhi
Phone 13825086505
Email zhimin@mail.sysu.edu.cn
Status Recruiting
Phase Phase 4
Start date January 15, 2022
Completion date January 15, 2025
View Details
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